Antioxidant activity in rat models of nociceptive stress.

Unlabelled: Pain is an important problem and has been the subject of many studies in recent years.

Material And Method: The present study has investigated the response of the antioxidant defense systems in contention stress, which mimics nociceptive stress. Contention stress was made by immobilizing the rat, Wistar rats, on an operating table in a specific position with paws tied, for thirty minutes.

The protective effect of montelukast sodium on carbon tetrachloride induced hepatopathy in rat.

Aim: This study investigates the effects of montelukast sodium (MK) (CysLTLT1 receptor antagonist) on CCl(4)induced hepatopathy on rat.

Material And Methods: We worked on 4 groups of 10 Wistar male rats each. The groups received as follows: group I (control group) - saline, group II - MK 5mg/kg/day i.