Sedentary Behaviour Among Male Adolescents in Sagamu, Southwest Nigeria.

Background: Sedentary behaviour (SB) is a leading risk factor for development of non-communicable diseases (NCDs) and associated morbidity worldwide. Several studies have reported a high prevalence of sedentary behaviour among adolescents in developing countries with a male preponderance. The Nigerian male adolescent is similarly faced with lifestyle challenges as his counterparts in other countries.

Post-partum mental disorders in Sagamu.

Background: Pregnancy and labour are sufficiently stressful to precipitate mental disorders in women after delivery. This may arise newly, as a recurrence or an exacerbation of previously existing mental illness in the individual woman. Postpartum mental disorders are under reported in our practices.

Selenium and aspirin in people living with HIV and AIDS in Nigeria.

Objectives: Aspirin and selenium have been shown in vitro and in vivo to inhibit HIV production through inhibition of the transcription factor, the nuclear factor kappa binding (NF-eB). The aim of this study was to examine the efficacy or otherwise of these drugs in people living with HIV and AIDS (PLWAS) in resource limited countries.

Patients And Methods: Consenting HAART-naive PLWAS with mean CD4 count of 256.

Endogenous antioxidant defences in plasma and erythrocytes of pregnant women during different trimesters of pregnancy.

Background: To assess the antioxidant capacity of pregnant women in Ogun State, Nigeria.

Methods: The activities of total superoxide dismutase (total SOD), manganese superoxide dismutase (Mn-SOD), catalase (CAT), glutathione transferase(GST), aminolevulinic acid dehydratase (ALAD), and the concentrations of glutathione (GSH), were determined in the plasma and red blood cells of non-pregnant (n=20), normal healthy pregnant women during different trimesters of pregnancy (n=90), and pregnant women with pre-eclampsia (n=7).

Results: A 2-fold increase in erythrocyte CAT activity was observed in the pregnant women (p<0.

Changing patterns of emergency obstetric care at a Nigerian University hospital.

Objective: To analyze the changing patterns of critical obstetric care over two consecutive 3-year periods and identify the factors responsible for the trend through combined audits of near miss and maternal mortality at a Nigerian University hospital.

Methods: Retrospective audit and comparison of "near misses" and maternal deaths recorded in 1999-2001 and 2002-2004 at a tertiary care center in southwest Nigeria. The definition of near miss morbidity was based on validated disease-specific criteria.

Effect of single administration of levonorgestrel on the menstrual cycle.

Background: Levonorgestrel (LNG) 1.5 mg administered within 72 h of unprotected coitus is an established method of emergency contraception. Currently, there is some, although incomplete, knowledge about the mechanism of action.

Nevirapine-related adverse events in a patient receiving a fixed-drug combination pill.

Nevirapine associated rash has been well described in the Caucasian population. With increasing access to antiretroviral treatment--especially a fixed dose combination--by people living with HIV/AIDS in developing countries, there is a need to emphasize the lead in doses of nevirapine. We strongly recommend a warning label on the bottle advising patients on the lead-in period and the signs and symptoms of significant rash.

Fertility desires and intentions of HIV-positive patients at a suburban specialist center.

Objectives: To determine the extent of fertility desires and intentions of HIV-positive patients receiving care at a suburban specialist clinic and assess how these may vary by their sociodemographic and health-related factors.

Methods: Questionnaire-based interview of a consecutive sample of HIV-positive men (18-55 years) and HIV-positive women (18-45 years) who presented at the HIV clinic of the Center for Special Studies, Sagamu, Nigeria, between November and December 2004.

Results: 63.

Spectrum and outcome of clinical diseases in adults living with AIDS at the Ogun State University Teaching Hospital.

Objectives: To evaluate the changing frequency of HIV/AIDS amongst medical admissions as well as the spectrum and outcome of clinical diseases among these patients.

Design: Retrospective study.

Setting: Tertiary hospital in Nigeria.

Cervical cancer screening at Ibadan.

Over a period of 44 months, 3171 smears were performed at the University College Hospital (UCH). Ibadan, Cytology Clinic. Of these, 44.