Publications by authors named "Odland I"

Background: Appropriate management of spontaneous intracerebral hemorrhage (ICH) and intraventricular hemorrhage (IVH) requires rapid, accurate volume estimation. Viz.AI has developed an artificial intelligence (AI)-powered ICH calculation tool that may improve existing methods.

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  • Surgical evacuation of intracerebral hemorrhage (ICH) performed early can lead to better functional outcomes, but doing it too quickly may cause significant risks like postoperative rebleeding.
  • The study developed a 5-point grading scale to assess the severity of intraoperative bleeding during minimally invasive endoscopic techniques for ICH evacuation.
  • Among 142 patients evaluated, results indicated that while early evacuation is associated with increased bleeding scores, it did not lead to worse long-term outcomes or increased postoperative rebleeding.
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  • Endovascular embolization is used as a supportive treatment for meningioma surgery, but evaluating its effectiveness is complicated because MRI scans are done before embolization and after the tumor is removed.
  • Researchers conducted a study using preoperative MRI after embolization to better measure how effective the procedure was, grading the extent of tumor devascularization and analyzing differences based on tumor location and blood supply.
  • The study found that the degree of devascularization correlated well with the volumetric extent of embolization, providing a clearer and more quantifiable way to assess the effectiveness of embolization before surgery.
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  • Preoperative embolization is an endovascular procedure that helps in the surgical removal of meningiomas but lacks a standardized system to measure its effectiveness during the procedure.
  • Researchers developed an angiographic grading system to help assess and report the level of tumor devascularization achieved through this process, involving a scale from 0 (no embolization) to 4 (complete embolization).
  • Analysis of data from 80 patients revealed that tumor location and the type of arterial feeders significantly influenced the success of embolization, with certain tumor types showing higher devascularization grades and a low complication rate of 2.5%.*
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High-grade gliomas (HGG) are the most common primary brain malignancy and continue to be associated with a dismal prognosis (median survival rate of 15-18 months) with standard of care therapy. Magnetic hyperthermia therapy (MHT) is an emerging intervention that leverages the ferromagnetic properties of magnetic iron-oxide nanoparticles (MIONPs) to target cancer cells that are otherwise left behind after resection. We report a novel port device to facilitate localization, delivery, and temperature measurement of MIONPs within a target lesion for MHT therapy.

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Background: Diffusion-weighted imaging (DWI) lesions have been linked to poor outcomes after intracerebral hemorrhage (ICH). We aimed to assess the impact of cerebral digital subtraction angiography (DSA) on the presence of DWI lesions in patients who underwent minimally invasive surgery (MIS) for ICH.

Methods: Retrospective chart review was performed on ICH patients treated with MIS in a single health system from 2015 to 2021.

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Background: Spontaneous intracerebral hemorrhage (ICH) can rapidly result in cerebral herniation, leading to poor neurologic outcomes or mortality. To date, neither decompressive hemicraniectomy (DH) nor hematoma evacuation have been conclusively shown to improve outcomes for comatose ICH patients presenting with cerebral herniation, with these patients largely excluded from clinical trials. Here we present the outcomes of a series of patients presenting with ICH and radiographic herniation who underwent emergent minimally invasive (MIS) ICH evacuation.

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Background: We explored the clinical significance of the residual hematoma cavity 1 year after minimally invasive intracerebral hemorrhage (ICH) evacuation.

Methods: Patients presenting with spontaneous supratentorial ICH were evaluated for minimally invasive surgical evacuation. Inclusion criteria included age ≥18 years, preoperative hematoma volume (Hv) ≥15 mL, presenting National Institutes of Health Stroke Scale score ≥6, and premorbid modified Rankin Scale (mRS) score ≤3.

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  • * Out of over 10 million AIS patients, about 9.2% had in-hospital dysphagia; for ICH, this was 10.2%, affecting patient outcomes such as mortality and discharge status.
  • * The study found that patients with dysphagia had longer hospital stays, were less likely to be discharged home, and incurred higher hospital charges, highlighting significant impacts on healthcare resources and patient recovery.
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  • The study investigates vocal fold paralysis (VFP) as a rare complication following acute ischemic stroke (AIS) and intracranial hemorrhage (ICH), aiming to assess its prevalence, characteristics, and in-hospital outcomes.
  • Out of over 10 million AIS patients, only 0.1% exhibited VFP, while 0.1% of ICH patients presented with this condition, revealing significant implications for hospital discharge and healthcare costs.
  • The findings indicate that patients with VFP post-AIS are less likely to be discharged home and incur higher hospital charges, while those with VFP post-ICH experience lower mortality but longer hospital stays and also face increased medical expenses.
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Objective: Neurosurgery residents face a learning curve at the beginning of residency. Virtual reality (VR) training may alleviate challenges through an accessible, reusable, anatomical model.

Methods: Medical students performed external ventricular drain placements in VR to characterize the learning curve from novice to proficient.

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  • Minimally invasive endoscopic evacuation for intracerebral hemorrhage (ICH) shows promise for improving patient outcomes, but it often leads to extended hospital stays, impacting costs.
  • In a study with 226 patients, key factors contributing to longer hospital stays included higher initial functional impairment, concurrent intraventricular hemorrhage, and deeper hematoma locations.
  • Prolonged hospital and ICU stays were linked to poorer discharge outcomes and decreased chances of recovery, suggesting that reducing LOS could enhance overall patient prognosis.
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  • Stroke is a major cause of death and disability, and this study explores the potential of exosomes as a new treatment method, using bibliometric analysis to track research trends.
  • Between 2010 and 2021, 424 documents were published, mainly from China and the US, with a clear yearly increase in research output, focusing on exosomes as pathogenic mediators, biomarkers, and treatments for stroke.
  • The findings highlight a significant interest in ischemic stroke studies, and suggest that future research should also investigate exosomes in other types of strokes, like intracerebral hemorrhage.
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Background: Stroke represents the second highest disease burden worldwide. It is well documented that rapid stroke identification and treatment are associated with improved outcomes. In particular, prehospital stroke detection (PSD) devices have emerged as possible tools to facilitate more rapid and accurate stroke triage.

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Background: Vagal nerve stimulation (VNS) has become established as an effective tool for the management of various neurologic disorders. Consequently, a growing number of VNS studies have been published over the past four decades. This study presents a bibliometric analysis investigating the current trends in VNS literature.

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Standard clinical care in neonatal and pediatric intensive-care units (NICUs and PICUs, respectively) involves continuous monitoring of vital signs with hard-wired devices that adhere to the skin and, in certain instances, can involve catheter-based pressure sensors inserted into the arteries. These systems entail risks of causing iatrogenic skin injuries, complicating clinical care and impeding skin-to-skin contact between parent and child. Here we present a wireless, non-invasive technology that not only offers measurement equivalency to existing clinical standards for heart rate, respiration rate, temperature and blood oxygenation, but also provides a range of important additional features, as supported by data from pilot clinical studies in both the NICU and PICU.

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The article presents the analysis of distribution of medical social characteristics and determinants of style of life of mothers in the groups with premature and urgent/delayed deliveries registered in the Register of deliveries of the Arkhangelsk oblast from 01.01.12 to 31.

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