Publications by authors named "Odile Pidoux"
Article Synopsis
- - This study focused on 15 infants under a year old in intensive care who were suspected to have genetic conditions and underwent rapid trio exome sequencing (rES) from April 2019 to April 2021.
- - The key finding was that results from rES were available to parents within 16 days for 86% of the participants, and 40% received a confirmed diagnosis.
- - The study highlights the potential of rES to enhance medical care for critically ill infants, despite some patients not receiving a diagnosis and a few passing away before results were available.
Objective: To evaluate the status of congenital diaphragmatic hernia (CDH) management in France and to assess predictors of adverse outcomes.
Study Design: We reviewed the first-year outcome of all cases of CDH reported to the French National Register in 2011.
Results: A total of 158 cases were included.
Background & Aims: Recent studies have suggested that the gut microflora has metabolic effects. We aimed to evaluate postnatal growth in preterm infants who received different probiotic supplements, and to assess the safety of probiotic administration.
Methods: This prospective, randomized, double-blind, controlled trial was performed at three tertiary care neonatal units.
A neonate with absent pulmonary valve syndrome (APVS) and features of tetralogy of Fallot presented respiratory distress. The prolonged need for mechanical ventilation was an indication for surgical repair. Preoperative thoracic CT imaging showed nearly complete closure of the distal trachea, compressed by the aneurysmal dilatation of the pulmonary arteries, and its reopening after ventilator pressure was increased.
View Article and Find Full Text PDFOrgan volume measurements: comparison between MRI and autopsy findings in infants following sudden unexpected death.
Arch Dis Child Fetal Neonatal Ed
November 2012
Objective: To assess the accuracy of a semiautomated 3D volume reconstruction method for organ volume measurement by postmortem MRI.
Methods: This prospective study was approved by the institutional review board and the infants' parents gave their consent. Postmortem MRI was performed in 16 infants (1 month to 1 year of age) at 1.
Objective: To compare the effects of nasal continuous positive airway pressure (nCPAP) and conventional oxygen therapy on the clinical signs of respiratory distress and the respiratory muscle workload in acute viral bronchiolitis.
Design: Prospective, randomized, monocentric study carried out in the pediatric intensive care unit (PICU) of a university hospital.
Patients: Infants <6 months old, admitted to the PICU with severe respiratory syncytial virus bronchiolitis.
Validation of a neonatal pain scale adapted to the new practices in caring for preterm newborns.
Arch Dis Child Fetal Neonatal Ed
July 2010
Unlabelled: BACKGROUND Neonatal pain assessment generally requires access to facial expression. Improved neonatology practices, such as greater protection against bright lights and non-invasive mask ventilation, have made facial observation more difficult.
Objective: To validate a 'faceless' acute neonatal pain scale (FANS), which does not depend on facial expression.
Objective: To evaluate growth and bone mineralization in very low birth weight (VLBW) infants fed preterm formula (PF) or term formula (TF).
Study Design: In a double-blind prospective study, 49 preterm infants of gestational age 33 weeks or less were randomly fed PF or TF for 2 months after discharge, then all of the infants were fed TF for the next 2 months. Anthropometric and dual-energy x-ray absorptiometry data were collected at discharge and at 2 months and 4 months after discharge.
Objective: To assess betamethasone (BM) effects on the cerebral hemodynamics of neonates with severe chronic lung disease (CLD).
Study Design: Intravenous BM was given once daily for 6 consecutive days to 12 infants (birth weight: 698 g [range, 650-884 g], gestational age: 25.3 weeks [range, 25-26.
Aim: To evaluate the administration of an equimolar mixture of N2O and O2 for intratracheal intubation in preterm neonates with respiratory distress syndrome (RDS).
Design: Prospective evaluation of N2O/O2 in premature neonates with RDS.
Setting: Tertiary neonatal unit from March to August 2003.