Background: Planned birth by induction of labour in low-risk, nulliparous women at 39-39 weeks gestation is associated with fewer caesarean sections, adverse maternal and neonatal outcomes and perinatal deaths compared with expectant management. However, the consequences of scheduled caesarean section in these women at this gestation are unclear. We compared outcomes following planned birth at 39-39 weeks gestation (either by induction of labour or scheduled caesarean section) to expectant management.
View Article and Find Full Text PDFThe number of retractions of randomized clinical trials (RCTs) following post-publication allegations of misconduct is increasing. To address this issue, we aimed to establish an international multistakeholder consensus on post-publication integrity concerns related to RCTs. After prospective registration (https://osf.
View Article and Find Full Text PDFPlacental dysfunction is a leading cause of numerous pregnancy complications, including preeclampsia, preterm birth, fetal growth restrictions, placental abruption, and late spontaneous abortion [...
View Article and Find Full Text PDFUltrasound Obstet Gynecol
January 2025
Objective: To compare the accuracy of four published reference standards for the umbilical artery pulsatility index (UA-PI) in predicting small-for-gestational age (SGA), adverse neonatal outcomes and obstetric complications in pregnancies at risk for fetal growth restriction.
Methods: This was a secondary analysis of a prospective study of singleton pregnancies that underwent fetal growth assessment by ultrasound between 26 and 36 weeks' gestation. Pregnancies with estimated fetal weight or abdominal circumference < 20 percentile with UA-PI measurements available were included.
Objective: Untreated opioid use disorder (OUD) is associated with significant morbidity in pregnancy. Recent reports have highlighted the rise of xylazine in the nonprescribed fentanyl supply. The frequency with which pregnant people with OUD are exposed to xylazine has not been characterized.
View Article and Find Full Text PDFAm J Obstet Gynecol MFM
December 2024
Objective: Physical activity in pregnancy decreases the risk of adverse maternal and neonatal outcomes. This study evaluates the association between first trimester physical activity, assessed by Kaiser Physical Activity Survey (KPAS) scores, and adverse perinatal outcomes.
Study Design: This is a secondary analysis of a prospective cohort study in which patients were administered the KPAS in each trimester.
Objective: The American College of Obstetricians and Gynecologists recommends speculum exams, rather than digital exams, for evaluation of the cervix after preterm prelabor rupture of membranes (PPROM). However, in clinical practice, digital exams may be necessary. We examined whether increasing numbers of digital exams were associated with adverse outcomes in PPROM.
View Article and Find Full Text PDFObjective: To predict birth weight at various potential gestational ages of delivery based on data routinely available at the first antenatal visit.
Design: Individual participant data meta-analysis.
Data Sources: Individual participant data of four cohorts (237 228 pregnancies) from the International Prediction of Pregnancy Complications (IPPIC) network dataset.
Am J Obstet Gynecol MFM
August 2024
Background: Both short and long interpregnancy intervals are associated with adverse pregnancy outcomes; however, the impact of interpregnancy intervals on labor progression is unknown.
Objective: We examined the impact of interpregnancy intervals on the labor curve, hypothesizing that those with a longer interpregnancy intervals would have slower labor progression.
Study Design: This is a retrospective cohort study of patients with a history of one prior vaginal delivery admitted for induction of labor or spontaneous labor with a singleton gestation ≥37 weeks at an academic medical center between 2004 and 2015.
Objectives: Estimated fetal weight (EFW) is an important metric at delivery as neonates with abnormal birthweight and their mothers are at higher risk of birth complications. Data regarding optimal EFW assessment in gravidas with obesity is inconsistent, and with the increasing incidence of obesity, clarification of this question is crucial. We aimed to compare accuracy of ultrasound (US)-derived EFW and clinical assessments of EFW in predicting neonatal birthweight among gravidas with obesity.
View Article and Find Full Text PDFBackground: There are limited data to guide the diagnosis and management of vasa previa. Currently, what is known is largely based on case reports or series and cohort studies.
Objective: This study aimed to systematically collect and classify expert opinions and achieve consensus on the diagnosis and clinical management of vasa previa using focus group discussions and a Delphi technique.
This study investigates nutrient recovery from synthetic municipal wastewater using co-immobilized cultures of Chlorella vulgaris TISTR 8580 (CV) and plant growth-promoting bacteria, Bacillus subtilis TISTR 1415 (BS) as living biofilters for a subsequent biofertilizer activity. The optimal condition for nutrient recovery was at the 1:1 ratio of CV/BS using mixed guar gum/carrageenan (GG/CG) binders. After 7-day wastewater treatment, the living biofilters removed 86.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
September 2024
Objective: Compared with postnatal repair, prenatal myelomeningocele (MMC) repair is associated with improved motor function and decreased need for cerebrospinal fluid (CSF) diversion. It is unknown how prenatal surgery alters neuroanatomical structures identifiable on magnetic resonance imaging (MRI). The purpose of this study was to use MRI to compare neurodevelopmental anatomy in patients undergoing fetal MMC repair compared with those undergoing postnatal repair.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
January 2024
Eur J Obstet Gynecol Reprod Biol
January 2024
Background: Hepatitis C infection often co-occurs with substance use disorders in pregnancy. Accessing hepatitis C treatment is challenging because of loss to follow-up in the postpartum period, attributable to social and financial barriers to care. Telemedicine has been explored as a means of increasing routine postpartum care, but the potential impact on retention in and completion of care for postpartum hepatitis C has not been assessed.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
March 2024
Objective: Fetoscopic laser photocoagulation (FLP) is a well-established treatment for twin-twin transfusion syndrome (TTTS) between 16 and 26 weeks' gestation. High-quality evidence and guidelines regarding the optimal clinical management of very early (prior to 16 weeks), early (between 16 and 18 weeks) and late (after 26 weeks) TTTS are lacking. The aim of this study was to construct a structured expert-based clinical consensus for the management of early and late TTTS.
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