Publications by authors named "Odianosen Ehiakhamen"

Article Synopsis
  • Nigeria reported its first mpox cases in nearly 40 years five years before the 2022-2023 outbreak, with ongoing human-to-human transmission driving the epidemic.
  • Researchers analyzed 112 mpox virus genomes from Nigeria (2021-2023) and traced the lineage back to its emergence around July 2014 from southern Nigeria, specifically Rivers State.
  • The study also found that human-to-human transmission significantly increased the virus's evolutionary rate and emphasized the importance of better pathogen surveillance and response strategies.
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Article Synopsis
  • Nigeria and Cameroon reported their first mpox cases in over 30 years starting in 2017 and 2018, with Nigeria's outbreak recognized as a human epidemic.
  • The study focused on understanding the zoonotic transmission dynamics of the mpox virus across the Nigeria-Cameroon border, revealing ongoing cases driven by a new Clade IIb.1 lineage and highlighting significant cross-border viral spread.
  • The findings indicate that southern Nigeria is likely the origin of the mpox epidemic, with evidence of a zoonotic precursor lineage present in local animal populations for over 45 years, emphasizing the persistent risk of MPXV emergence in both countries.
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Background: We describe diverse clinical characteristics and course of confirmed mpox cases managed in a Nigerian tertiary health facility.

Methods: Clinical and epidemiologic data were analyzed, highlighting the unusual presentations of polymerase chain reaction (PCR)-confirmed mpox cases observed during the 2022 outbreak.

Results: Out of 17 suspected cases, 13 (76.

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Background: We describe clinicoepidemiologic characteristics of mpox-chickenpox coinfection in Nigeria.

Methods: A retrospective cohort analysis was performed of confirmed mpox cases in Nigeria from January 2022 to March 2023. Mpox and chickenpox were confirmed by real-time polymerase chain reaction (RT-PCR).

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Article Synopsis
  • Monkeypox (MPX) is a rare viral disease similar to smallpox, with sporadic outbreaks in Nigeria since 2017, worsened by the COVID-19 pandemic impacting disease monitoring.
  • This study aimed to enhance the surveillance of MPX in three priority states (Rivers, Delta, and Bayelsa) by training community volunteers to actively search for cases over a three-month period.
  • The enhanced surveillance led to the identification of 25 suspected MPX cases, with 3 confirmed positives, demonstrating that better monitoring can significantly improve reporting and response to the disease in affected areas.
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