Publications by authors named "Odette Nemelka"
Malformations following methimazole exposure in utero: an open issue.
Silvio Ferraris Mariella Valenzise Margherita Lerone Maria Teresa Divizia Lucia Rosaia Odette Nemelka
Birth Defects Res A Clin Mol Teratol
December 2003
Article Synopsis
- In pregnancies complicated by hyperthyroidism, treatment with propylthiouracil (PTU) or methimazole (MMI) is necessary to maintain normal thyroid function.
- Both medications are effective but can pose risks of fetal and neonatal hypothyroidism due to their ability to cross the placenta, with MMI potentially linked to specific birth defects.
- The report suggests using PTU as the preferred option and limiting MMI to cases where PTU cannot be used due to allergies or ineffectiveness.