Synopsis of recent research by authors named "Odena Vilalta"
- Odena Vilalta's research primarily focuses on understanding the onset and development of low-flow vascular malformations, which are linked to congenital overgrowths of abnormal blood vessels.
- The findings indicate that these malformations are associated with oncogenic mutations in endothelial cells leading to the overactivation of the PI3K/AKT signaling pathway during angiogenesis.
- A notable aspect of the research is the demonstration that the AKT inhibitor miransertib can prevent the onset of these malformations, highlighting its potential as a therapeutic option for conditions currently lacking effective treatments.
