Publications by authors named "Od Bayarsaikhan"

Background/purpose: Patients' considerations when choosing an orthodontist are influenced by many factors, including background, ethnicity, and location. Accordingly, this study aimed to identify factors influencing patients' considerations when selecting an orthodontist in both Malaysia and Taiwan.

Materials And Methods: In total, 248 dental students from Taipei Medical University and 110 dental students from Manipal University College Malaysia were selected for this study.

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Article Synopsis
  • The study focuses on assessing the need for orthodontic treatment among schoolchildren in Ulaanbaatar, Mongolia, as malocclusion rates are rising.
  • A total of 656 children aged 9-12 from 8 schools were evaluated using the Index of Orthodontic Treatment Need (IOTN), which includes Dental Health Component (DHC) and aesthetic component (AC) assessments.
  • Results showed that 84.5% of children had malocclusions, with around one-third needing orthodontic treatment, highlighting a significant oral health issue and informing dental care planning.
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Myostatin, a member of the TGF-β superfamily, is a negative regulator of skeletal muscle cell growth and differentiation, and binds with high affinity to the activin type IIB receptor (ActRIIB). The soluble ligand-binding domain of ActRIIB fused to the Fc domain of IgG (ActRIIB-Fc) potently binds and inhibits TGF-β family members in muscle, leading to rapid and marked muscle growth. The present study was designed to assess the effectiveness of the co-delivery of myostatin-targeting siRNA (Mstn-siRNA) and ActRIIB-Fc into skeletal muscle as a potential treatment of atrophic myopathies.

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