Energetics and the molecular structure of an ion-paired supramolecular system in water.

The forces that bind the components of a host-guest complex to generate a stable supramolecular system are noncovalent interactions. The enthalpy of this association, ΔH°, usually measured using calorimetry, quantifies the magnitude of such interactions and is directly related to the stability of the supramolecular complex formed. Using Calvet calorimetry to determine the enthalpies of solution and reaction in water, the enthalpy of association was derived for a supramolecular system formed by the anionic macrocycle anti-disulfodibenzo[24]crown-8 ([DSDB24C8]) and the dicationic guest paraquat [PQT].