Publications by authors named "Ochi A"

The mechanisms underlying the maintenance of hypertension in renovascular hypertension (RVH) are not well understood. To test the current concept of RVH pathophysiology, circulating aldosterone levels in clinical cases were investigated through a literature survey of pediatric cases. Fifty-four patients with documented aldosterone levels were identified.

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Autoimmune hypothyroidism is categorized into Hashimoto thyroiditis (HT) and atrophic thyroiditis (AT). Although a consensus exists among Japanese endocrinologists that pediatric AT is associated with severe hypothyroidism, the question remains whether AT and HT are separate conditions. To investigate the clinical characteristics of pediatric AT, we conducted a comprehensive literature review using PubMed and ICHUSHI, a local database.

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High-energy nuclear collisions create a quark-gluon plasma, whose initial condition and subsequent expansion vary from event to event, impacting the distribution of the eventwise average transverse momentum [P([p_{T}])]. Disentangling the contributions from fluctuations in the nuclear overlap size (geometrical component) and other sources at a fixed size (intrinsic component) remains a challenge. This problem is addressed by measuring the mean, variance, and skewness of P([p_{T}]) in ^{208}Pb+^{208}Pb and ^{129}Xe+^{129}Xe collisions at sqrt[s_{NN}]=5.

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Introduction: This study investigated low-density scalp electrical source imaging of the ictal onset zone and interictal spike ripple high-frequency oscillation networks using source coherence maps in the pediatric epilepsy surgical workup. Intracranial monitoring, the gold standard for determining epileptogenic zones, has limited spatial sampling. Source coherence analysis presents a promising new non-invasive technique.

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Cholesterol metabolism is associated with innate immune responses; however, the underlying mechanism remains unclear. Here, we perform chemical screening to isolate small molecules influencing RIG-I activity, a cytoplasmic viral RNA sensor. We find that statins, which inhibit cholesterol synthesis, dramatically enhance RIG-I-dependent antiviral responses in specific cell types.

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Objectives: Abusive Head Trauma (AHT) remains an important cause of acute seizures, morbidity, and mortality in children. We aimed to assess the clinical and electrographic seizure burden in children with AHT and to explore predictors of morbidity and mortality.

Methods: We conducted a retrospective chart review of all children admitted with AHT who underwent continuous electroencephalographic monitoring (cEEG) between January 1st, 2015, and April 15th, 2021.

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Introduction: A retroperitoneoscopic procedure for bladder neck closure has not yet been described.

Case Presentation: Case 1 was a 56-year-old man who underwent clean intermittent catheterization for spastic paraplegia due to a thoracic spinal cord injury 37 years prior. Case 2 was an 80-year-old bedridden woman who underwent urethral catheterization after a femoral fracture and brain infarction 3 years prior.

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A search for the exclusive hadronic decays W^{±}→π^{±}γ, W^{±}→K^{±}γ, and W^{±}→ρ^{±}γ is performed using up to 140  fb^{-1} of proton-proton collisions recorded with the ATLAS detector at a center-of-mass energy of sqrt[s]=13  TeV. If observed, these rare processes would provide a unique test bench for the quantum chromodynamics factorization formalism used to calculate cross sections at colliders. Additionally, at future colliders, these decays could offer a new way to measure the W boson mass through fully reconstructed decay products.

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Article Synopsis
  • - The ATLAS experiment at the LHC conducted a search for long-lived particles (LLPs) using a large dataset (140 fb^{-1}) from proton-proton collisions at 13 TeV, focusing on LLPs with masses from 5 to 55 GeV that decay within the inner detector.
  • - The study considered scenarios where LLPs are produced from exotic Higgs boson decays and models involving axionlike particles (ALPs).
  • - No significant findings above expected background levels were detected, leading to the establishment of upper limits on various production rates involving the Higgs boson and the top quark related to LLPs and ALPs.
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  • The study investigates the associated production of Higgs and W bosons, focusing on how the relative signs of the Higgs couplings to W and Z bosons impact the process.
  • Two specific searches were conducted using large amounts of collision data from the LHC to analyze different coupling scenarios: one for opposite-sign couplings and another for same-sign (standard model-like) couplings.
  • The results significantly exclude the opposite-sign coupling hypothesis and set a strict upper limit on the production rate of this process compared to standard model predictions.
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In this study, equine intestinal enteroids (EIEs) were generated from the duodenum, jejunum, and ileum and inoculated with equine coronavirus (ECoV) to investigate their suitability as in vitro models with which to study ECoV infection. Immunohistochemistry revealed that the EIEs were composed of various cell types expressed in vivo in the intestinal epithelium. Quantitative reverse-transcription PCR (qRT-PCR) and virus titration showed that ECoV had infected and replicated in the EIEs.

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  • * He was diagnosed with acute heart failure and infective endocarditis (IE), but due to his age and surgical history, surgery was deemed too risky.
  • * Instead of surgery, the team performed lead extraction, inserted a leadless pacemaker, and provided antimicrobial therapy, leading to the patient's discharge after 48 days, showcasing a less invasive strategy for treating device-related infections.
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Unlike the previous literature on climate change, this study employed the panel vector autoregressive model to examine the impact of population growth, governance quality, and economic growth on global warming. Moreover, we used the impulse response function tool, which was developed in the same context, to better understand the reaction of the main variables of interest, per capita greenhouse gas (GHG) emissions, aftershocks on population change, governance quality, and economic growth variables. Finally, the analysis was completed by the variance decomposition of all variables.

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This Letter presents results from a combination of searches for Higgs boson pair production using 126-140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV recorded with the ATLAS detector. At 95% confidence level (CL), the upper limit on the production rate is 2.9 times the standard model (SM) prediction, with an expected limit of 2.

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This Letter presents the first study of the energy dependence of diboson polarization fractions in WZ→ℓνℓ^{'}ℓ^{'}(ℓ,ℓ^{'}=e,μ) production. The dataset used corresponds to an integrated luminosity of 140  fb^{-1} of proton-proton collisions at a center-of-mass energy of 13 TeV recorded by the ATLAS detector. Two fiducial regions with an enhanced presence of events featuring two longitudinally polarized bosons are defined.

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Unlabelled: Equine piroplasmosis (EP) is a protozoal disease affecting equids, caused by and . EP is conventionally diagnosed using microscopic, molecular, and/or serological methods, which are time-consuming. Consequently, there is a need for faster testing methods.

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Article Synopsis
  • The study focused on serum SDC-1 concentration, a marker of endothelial glycocalyx degradation, and its relationship with albuminuria in type 2 diabetes patients.
  • Researchers included 370 people with type 2 diabetes and found that those with diabetes had higher serum SDC-1 levels compared to non-diabetic individuals.
  • The results indicated that higher serum SDC-1 was independently linked to increased urinary albumin-to-creatinine ratio, suggesting a connection between endothelial glycocalyx degradation and albuminuria in diabetes.
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Statistical combinations of searches for charginos and neutralinos using various decay channels are performed using 139  fb^{-1} of pp collision data at sqrt[s]=13  TeV with the ATLAS detector at the Large Hadron Collider. Searches targeting pure-wino chargino pair production, pure-wino chargino-neutralino production, or Higgsino production decaying via standard model W, Z, or h bosons are combined to extend the mass reach to the produced supersymmetric particles by 30-100 GeV. The depth of the sensitivity of the original searches is also improved by the combinations, lowering the 95% C.

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  • The study investigates the effects of Xanthine oxidoreductase (XOR) inhibitors on insulin secretion in patients with type 2 diabetes, highlighting that these inhibitors can improve glycemic control and ATP synthesis.
  • A total of 428 patients were analyzed, with XOR inhibitor users showing significantly higher insulin secretory capacity compared to non-users, as measured by C-peptide levels.
  • The findings suggest that XOR inhibitors may offer protective benefits for insulin secretion, particularly in patients with lower serum uric acid levels, although no link to insulin resistance was found.
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  • * The measurements utilized both semileptonic and hadronic decays of top quarks, along with events focused on single top quark production in the electroweak t channel.
  • * The combined result for the top quark mass is 172.52 GeV, with a reduced total uncertainty of 0.33 GeV, showcasing an improvement of 31% over previous measurements.
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A combination of searches for a new resonance decaying into a Higgs boson pair is presented, using up to 139  fb^{-1} of pp collision data at sqrt[s]=13  TeV recorded with the ATLAS detector at the LHC. The combination includes searches performed in three decay channels: bb[over ¯]bb[over ¯], bb[over ¯]τ^{+}τ^{-}, and bb[over ¯]γγ. No excess above the expected Standard Model background is observed and upper limits are set at the 95% confidence level on the production cross section of Higgs boson pairs originating from the decay of a narrow scalar resonance with mass in the range 251 GeV-5 TeV.

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Higgsinos with masses near the electroweak scale can solve the hierarchy problem and provide a dark matter candidate, while detecting them at the LHC remains challenging if their mass splitting is O(1  GeV). This Letter presents a novel search for nearly mass-degenerate Higgsinos in events with an energetic jet, missing transverse momentum, and a low-momentum track with a significant transverse impact parameter using 140  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV collected by the ATLAS experiment. For the first time since LEP, a range of mass splittings between the lightest charged and neutral Higgsinos from 0.

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  • GoxSSAR and AacGR are two special enzymes that belong to a group called β-hydroxyacid dehydrogenases.
  • GoxSSAR can work with two substances: glyoxylate and succinic semialdehyde, while AacGR can only work with glyoxylate.
  • Scientists found that changing certain parts of these enzymes affected how well they worked, showing how they are both similar and different.
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Angular correlations between heavy quarks provide a unique probe of the quark-gluon plasma created in ultrarelativistic heavy-ion collisions. Results are presented of a measurement of the azimuthal angle correlations between muons originating from semileptonic decays of heavy quarks produced in 5.02 TeV Pb+Pb and pp collisions at the LHC.

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  • Outcomes from vagus nerve stimulation (VNS) improve over time in children with drug-resistant epilepsy, but the benefits of deep brain stimulation (DBS) versus continued VNS optimization were unclear.
  • A study involving 18 children aged 8-17 showed that adding DBS after a year of ineffective VNS led to significantly greater seizure reduction (51.9% vs. 12.3%).
  • While DBS resulted in fewer bothersome seizures, it did not improve the overall quality of life, suggesting that earlier consideration of DBS could be beneficial for children not responding to VNS.
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