Publications by authors named "Oceane Pecheux"

Article Synopsis
  • The concept of advanced maternal age (AMA) often refers to women aged 35 and older, with the global standard set at 40 years for monitoring and delivery timelines.
  • Mothers with AMA are more likely to have health issues like type 2 diabetes and hypertension, which increases the chances of complications during pregnancy.
  • Risks associated with AMA include higher rates of miscarriage, gestational diabetes, caesarean sections, and potential fetal issues like genetic anomalies and prematurity.
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The apelinergic system is a highly conserved pleiotropic system. It comprises the apelin receptor apelin peptide jejunum (APJ) and its two peptide ligands, Elabela/Toddler (ELA) and apelin, which have different spatiotemporal localizations. This system has been implicated in the regulation of the adipoinsular axis, in cardiovascular and central nervous systems, in carcinogenesis, and in pregnancy in humans.

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Introduction: Hereditary hypofibrinogenemia is a rare fibrinogen disorder characterised by decreased levels of fibrinogen. Pregnant women with hypofibrinogenemia are at risk of adverse obstetrical outcomes, depending on the fibrinogen level.

Aim: We investigated how the physiological changes of hemostasis throughout the pregnancy impact the hemostatic balance in a woman with hereditary mild hypofibrinogenemia.

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Cytomegalovirus infection remains the main congenital infectious cause of abnormal development, notably neurological or auditory. In case of early maternal infection, vertical transmission is lower than later in pregnancy, but fetal/neonatal sequelae are more frequent and severe. Until recently, there was no available treatment to prevent transmission and complications and only preventive measures were recommended.

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Article Synopsis
  • The APJ receptor and its ligands, apelin and elabela, are important for the development of the fetus and placenta.
  • In a study comparing obese and non-obese mothers, researchers found that obesity specifically lowered apelin levels in the cord blood of newborns.
  • However, obesity did not impact levels of elabela in either maternal plasma or cord blood, nor did it change the expression of related genes in the placenta.
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Article Synopsis
  • A French certification for gynecological cancer surgery was introduced in 2021 to ensure trainees develop necessary skills through practical and theoretical training.
  • A national study surveyed 125 gynecology trainees about their training experiences and views on the certification, revealing that a significant majority (66.1%) aim to specialize in surgical oncology.
  • Despite interest in certification, trainees reported feeling inadequately prepared, with concerns about regional disparities affecting their access to specialized training opportunities.
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Objective: Post-operative CRP on postoperative day 4 (POD) is used for the early detection of complications after colorectal surgery for cancer, but there is no evidence yet that justifies the use of this marker for bowel resection in case of endometriosis.

Study Design: We retrospectively included 66 consecutive patients who underwent bowel resection for endometriosis (stage 4) in Lille university hospital, France, from August 1, 2015 until January 31, 2017. The composite endpoint of our study included anastomotic leakages, infectious or thrombo-embolic complications, hematomas, bowel stenosis, rectorrhagia, voiding dysfunction, and rehospitalization for related symptoms.

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Objective: The Institute of Medicine (IOM) recommended a gestational weight gain for full-term twin pregnancies of 17-25 kg for normal Body mass Index patients', and characterize its guidelines on during twin pregnancies as "provisional". Indeed, they are exclusively based on observational epidemiological data. The objective of this study was to investigate whether the IOM's gestational weight gain guidelines are optimal for maternal and neonatal.

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Objective: Polypropylene meshes have specific complications, and in 2016 the Food and Drug Administration required a Premarket Approval for their use in pelvic prolapse repair, as there was a lack of long-term data. Our objectives were to determine the long-term reoperation rates and type in our patients after transvaginal mesh repair and to study their risk factors.

Study Design: We were able to follow up with 349 patients from a single University Hospital, with phone calls, after a median time of 8,5 years.

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