Publications by authors named "Obieda Altobaishat"

Background: Rotational atherectomy (RA) has been proven to treat coronary artery calcification (CAC) during percutaneous coronary intervention (PCI).

Purpose: This study evaluates the safety and efficacy of RA followed by cutting balloon angioplasty (ROTACUT) before stent placement in CAC.

Methods: A systematic review and meta-analysis of randomized controlled trials and observational studies was conducted.

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Background: Helicobacter pylori (H. pylori) infection increases the risks of chronic gastritis, peptic ulcer diseases, and the incidence of gastric cancer. However, antibiotic resistance and adverse effects led to the emergence of alternative treatments such as probiotics supplementation.

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Transcatheter aortic valve replacement has emerged as an effective alternative to surgery in selected patients with aortic stenosis. It needs to be made clear which type of valve has better results in patients with small aortic annulus. We searched PubMed, Scopus, Embase, Cochrane Library, and Web of Science, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement.

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Article Synopsis
  • The study investigates the impact of single arterial cannulation (SAC) versus double arterial cannulation (DAC) during repairs for acute type A aortic dissection, focusing on patient outcomes such as hospital stay and complications.
  • A systematic review of 7 studies involving 3,534 patients revealed that DAC led to longer stays in intensive care but did not significantly affect overall length of hospital stay or rates of stroke, paraplegia, or acute kidney injury compared to SAC.
  • The findings suggest that while DAC could be associated with higher risks of complications like need for dialysis or reintubation, overall clinical outcomes remain comparable, underscoring the importance of individualized cannulation strategies for patients.*
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Article Synopsis
  • - Cardiac transplantation in the MENA region has improved since its beginnings in 1967, with advancements in surgical techniques and patient care, but still faces unique challenges due to cultural, economic, and infrastructural factors.
  • - Research shows that countries like Saudi Arabia, the UAE, and Lebanon have established cardiac transplant programs, and new technologies like ex-vivo perfusion are enhancing outcomes, yet issues such as organ shortages and varying healthcare resources remain significant obstacles.
  • - To boost cardiac transplantation rates, there's a need for better public awareness, consistent healthcare protocols, and development of regional networks, along with innovations in immunosuppressive therapies and organ preservation techniques.
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Objectives: To determine whether clinical decision support systems (CDSS) for acute kidney injury (AKI) would enhance patient outcomes in terms of mortality, dialysis, and acute kidney damage progression.

Methods: The systematic review and meta-analysis included the relevant randomized controlled trials (RCTs) retrieved from PubMed, EMBASE, Web of Science, Cochrane, and SCOPUS databases until 21st January 2024. The meta-analysis was done using (RevMan 5.

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Background: Prevention and treatment of the monkeypox virus (Mpox) remain challenging in areas where it is endemic. This systematic review and meta-analysis aimed to collect this information from various studies in one study to give a comprehensive view of people's opinions, fears, and behaviors about this virus.

Methods: We searched PubMed, Scopus, Web of Science, the Cochrane Library, and Google Scholar for descriptive cross-sectional study designs conducted in 2022 and 2023 addressing knowledge, attitude, perception, preparedness, willingness to get vaccinated, and practices against Mpox infection.

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Background: Clinical decision support systems (CDSS) have been utilized as a low-cost intervention to improve healthcare process measures. Thus, we aim to estimate CDSS efficacy to optimize adherence to oral anticoagulant guidelines in eligible patients with atrial fibrillation (AF).

Methods: A systematic review and meta-analysis of randomized controlled trials (RCTs) retrieved from PubMed, WOS, SCOPUS, EMBASE, and CENTRAL through August 2023.

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Introduction: Growth hormone deficiency occurs when the pituitary gland does not produce enough growth hormone. Norditropin®, a recombinant human growth hormone, and Sogroya®, an albumin-binding growth hormone derivative, are prescribed for patients with growth hormone deficiency. This systematic review assesses the efficacy, safety, and patient satisfaction associated with Norditropin and Sogroya.

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Introduction: Postoperative cognitive dysfunction (POCD) is a common neurological issue following cardiopulmonary bypass (CPB)-assisted heart surgery. Remote ischemic preconditioning (RIPC) increases the tolerance of vital organs to ischemia/reperfusion injury, leading to reduced brain injury biomarkers and improved cognitive control. However, the exact mechanisms underlying RIPC's neuroprotective effects remain unclear.

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Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent metabolic disorder characterized by excessive hepatic fat accumulation. Intermittent fasting (IF) has emerged as a potential therapeutic strategy with the ability to induce weight loss, improve insulin sensitivity and reduce hepatic steatosis. We aim to compare the efficacy of different IF regimens for MASLD management.

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Article Synopsis
  • - This systematic review compared transcatheter aortic valve implantation (TAVI) and surgical aortic valve replacement (SAVR) specifically for patients with pure aortic regurgitation, highlighting conflicting previous studies.
  • - The analysis included data from six studies involving over 33,000 patients and found comparable in-hospital mortality rates but significantly lower rates of stroke, acute kidney injury, and major bleeding with TAVI.
  • - Although TAVI led to better safety outcomes and shorter hospital stays, it also resulted in a higher rate of pacemaker implantation compared to SAVR.
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Background And Objective: Quadpill, a single pill containing a quadruple combination of quarter doses of four antihypertensive agents, has been investigated for hypertension treatment. This meta-analysis aims to evaluate the safety and efficacy of quadpill for hypertension management.

Methods: We conducted a systematic review and meta-analysis synthesizing randomized controlled trials evaluating quadpill versus monotherapy or placebo in patients with hypertension, which were retrieved by systematically searching PubMed, EMBASE, Web of Science, SCOPUS, and Cochrane through 17 February, 2023.

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