Background: Rifampicin, an antibiotic used in the treatment of tuberculosis has raised concerns about its potential liver and kidney toxicity.
Aim: This study aimed to evaluate the protective effects of Aloe vera against hepatorenal toxicity induced by rifampicin in male Wistar rats.
Methods: Thirty rats were divided into six groups (n = 5): group A (control), group B treated with rifampicin, groups C-E treated with varying doses (50, 100, and 200 mg/kg) of Aloe vera alongside rifampicin as well as a group F treated with furosemide and rifampicin for a total of 30 days.