[Scaffolds based on collagen and chitosan for post-burn tissue engineering].

Unlabelled: Porous scaffolds based on collagen and chitosan have been obtained from mixed bio-polymeric solutions and mixture freeze-drying method in the purpose of using them as materials for post-burns tissue regeneration.

Material And Method: Soluble collagen from bovine leather was obtained by acid-base extraction (isoelectric pH = 4.82).

Functionalized chitosan/NIPAM (HEMA) hybrid polymer networks as inserts for ocular drug delivery: synthesis, in vitro assessment, and in vivo evaluation.

A series of hybrid polymeric hydrogels, prepared by the reaction of acrylic acid-functionalized chitosan with either N-isopropylacrylamide or 2-hydroxyethyl methacrylate monomers, were synthesized, pressed into minitablets, and investigated for their ability to act as controlled release vehicles for ophthalmic drug delivery. For comparison, interpolymeric complex analogues synthesized using the same monomers and pure, unfunctionalized chitosan were examined by means of an identical characterization protocol. The effects of network structure and composition upon the swelling properties, adhesion behavior, and drug release characteristics were investigated.