Value of endometrial biopsy in patients with hysteroscopically atrophic endometrium in patients with postmenopausal bleeding.

Purpose: To determine the rate of precancer and cancer in women presenting with PMB who have a visually atrophic endometrium at hysteroscopy and assess the value of endometrial biopsy in this situation and the adequacy of the samples obtained.

Methods: Retrospective reviews of all patients with a visually atrophic endometrium at hysteroscopy who had presented with PMB and had an ET > / = 4 mm or ET < 4 mm with focal changes or irregular features between 2013 and 2024 at University Hospitals of Derby and Burton were included (n = 1096). Patients who had previously had cancer or precancer or had unclear hysteroscopy findings were excluded.

A finite volume adaptation of beam-to-beam contact interactions implemented for geometrically exact Simo-Reissner beams.

This paper presents an adaption of the finite-element based beam-to-beam contact interactions into a finite volume numerical framework. A previous work of the same authors, where a cell-centred based finite volume implementation of geometrically exact nonlinear Simo-Reissner beams was developed, is used as an underlying mathematical model. An implicit contact procedure is developed for both point-to-point and line-to-line beam frictionless contact interactions, and is implemented using the cell-centred finite volume method.

Near-Complete Avipoxvirus Genome Assembled from Skin Lesions of Dead Eurasian Crane ().

Avian pox is a globally spread viral disease affecting a wide spectrum of wild and domesticated bird species. The disease is caused by a diverse group of large DNA viruses, namely, avipoxviruses (genus , family ). In this study, gross pathological examination and histopathological examination of skin lesions and several organs suggested acute poxvirus infection of a Eurasian crane (, Linnaeus, 1758).

Corrigendum: Investigating antimicrobial resistance genes in probiotic products for companion animals.

[This corrects the article DOI: 10.3389/fvets.2024.

Maternity Care Experiences of African-Born Women Living in Melbourne, Australia: A Qualitative Descriptive Study.

Background: African-born women in Australia are more likely to experience poorer perinatal outcomes than their Australian-born counterparts. This disparity may be attributed to difficulties in accessing maternity care services. With a rapidly growing African-born population in Australia, understanding African-born women's experiences with maternity care is crucial for ensuring equitable access.

Calmodulin binding is required for calcium mediated TRPA1 desensitization.

Calcium (Ca) ions affect nearly all aspects of biology. Excessive Ca entry is cytotoxic and Ca-mobilizing receptors have evolved diverse mechanisms for tight regulation that often include Calmodulin (CaM). TRPA1, an essential Ca-permeable ion channel involved in pain signaling and inflammation, exhibits complex Ca regulation with initial channel potentiation followed by rapid desensitization.

Early Intervention in Post-operative Infectious Spondylodiscitis: Outcome of Aggressive Transforaminal Lumbar Interbody Fusion.

Introduction: Conservative and surgical approach timeline in post-operative spondylodiscitis (POS) following lumbar disc herniation (LDH) surgery is ill defined, and patients have a protracted recovery phase with social, psychological, and financial implications.

Material And Methods: Retrospective analysis of patients operated by transforaminal lumbar interbody fusion (TLIF) in POS was done. Confirmed clinico-radiological diagnosed POS cases, not responding within three to four weeks were included.

Feline Adenovirus Isolate Shows Silent Nucleotide Alterations, Alternative Receptor/Coreceptor Binding, High Resistance to Disinfectants and Antiviral Drugs, as Well as Immunomodulation.

Adenovirus (AdV) infection has been rarely documented in cats and other felids. Partial sequences of the hexon and fiber genes of a Hungarian feline adenovirus isolate (FeAdV isolate) showed a close relationship to human AdV (HAdV) type C1. Further molecular and biological characterization is reported here.

Perceptions and attitudes regarding robotic total hip arthroplasty: a patient stakeholder survey.

To describe the attitudes and preferences of patients pertaining to robotic-assisted total hip arthroplasty (RA-THA) with the long-term objective of designing a prospective randomized-controlled trial (RCT) to evaluate the efficacy of RA-THA compared to conventional technique. A cross-sectional survey of patients attending an outpatient high-volume academic arthroplasty clinic chosen was administered from December 2023 to May 2024. The survey comprised 31 items including patient demographic, patient reported factors of significance and perceptions surrounding RA-THA.

"Sentio ergo est": Unmasking the psychological realities of emotional misperception.

Perception is an important aspect of our personal lives, interpersonal interactions and professional activities and performance. A large body of psychological research has been dedicated to exploring how perception happens, whether and when it involves conscious awareness and what are the physiological correlates, such as skin-conductance and heart-rate responses, that occur when we perceive particularly emotional elicitors. A more recent and less explored question in psychological science is how and when misperception happens, and what are the physiological characteristics of the misperception of emotion.

King Abdulaziz University Hospital Capsule dataset: A novel small-bowel endoscopic image repository from Saudi Arabia.

Wireless Capsule Endoscopy (WCE) has fundamentally transformed diagnostic methodologies for small-bowel (SB) abnormalities, providing a comprehensive and non-invasive gastrointestinal assessment in contrast to conventional endoscopic procedures. The King Abdulaziz University Hospital Capsule (KAUHC) dataset comprises annotated WCE images specifically curated for Saudi Arabian residents. Comprising 10.

Yin Yang 1 and guanine quadruplexes protect dopaminergic neurons from cellular stress via transmissive dormancy.

Neurons deploy diverse adaptive strategies to ensure survival and neurotransmission amid cellular stress. When these adaptive pathways are overwhelmed, functional impairment or neurodegeneration follows. Here we show that stressed neurons actively induce a state of transmissive dormancy as a protective measure.

Effect of pregnancy intention on completion of maternity continuum of care in Sub-Saharan Africa: systematic review and meta-analysis.

Background: The maternity continuum of care is a strategy to provide timely and quality maternal and child healthcare through preconception, pregnancy, childbirth, postnatal, and the early childhood periods. The maternity continuum of care effectively reduces global maternal and neonatal deaths. However, several factors are reported to cause low completion of the maternity continuum of care in sub-Saharan Africa.

Precision in Prosthetics: Two Case Reports on Transformative Rehabilitation With Custom Ocular and Orbital Prostheses.

The eyes play a crucial role in vision and emotional expression, and their loss can profoundly affect appearance and psychological well-being. Eye loss may result from trauma, tumors, infections, malignancies, or congenital abnormalities. Surgical methods for removing an eye include enucleation, evisceration, and exenteration.

What Is the Role of the Gut Microbiota in Anastomotic Leakage After Colorectal Resection? A Scoping Review of Clinical and Experimental Studies.

Anastomotic leakage (AL) still remains a common complication after colorectal anastomosis that leads to increased morbidity and mortality. The gut microbiota has been hypothesized as one of the risk factors associated with anastomotic leakage. The aim of the present study was to summarize all existing clinical and experimental studies that evaluate the impact of intestinal microbiota on anastomotic leakage after colorectal resection.

Endoscopic In Vivo Hyperspectral Imaging for Head and Neck Tumor Surgeries Using a Medically Approved CE-Certified Camera with Rapid Visualization During Surgery.

: In vivo visualization of malignant tumors remains the main challenge during head and neck cancer surgery. This can result in inadequate tumor margin assessment and incomplete tumor resection, adversely affecting patient outcomes. Hyperspectral imaging (HSI) is a promising approach to address this issue.

Differential Gene Expression and Transcriptomics Reveal High M-Gene Expression in JN.1 and KP.1/2 Omicron Sub-Variants of SARS-CoV-2: Implications for Developing More Sensitive Diagnostic Tests.

SARS-CoV-2, a positive-strand RNA virus, utilizes both genomic replication and subgenomic mRNA transcription. Whole genome sequencing (WGS) from clinical samples can estimate viral gene expression levels. WGS was conducted on 529 SARS-CoV-2 positive clinical samples from Assam and northeastern India to track viral emergence and assess gene expression patterns.

A Case Report of Deterioration in a Non-frail Octogenarian Burn Patient.

While advancements in critical care and burn treatment have improved over the decades, elderly burn victims continue to face high mortality rates. Measurements of frailty among patients have become popular tools for predicting burn outcomes over chronological age. In this report, we provide a case of a non-frail octogenarian burn victim who deteriorated rapidly during treatment, suggesting that frailty alone is not sufficient in predicting outcomes in older burn patients.