Embryotoxicity Evaluation of Novel Synthetic Cannabinoid 4F-MDMB-BUTICA Using Zebrafish Embryos.

Detailed studies on the embryotoxic and teratogenic effects of synthetic cannabinoids known to be abused are very limited. The present study aimed to evalutate the possible embryotoxic, teratogenic, behavioral, and molecular effects of 4F-MDMB-BUTICA, a new generation synthetic cannabinoid, using zebrafish embryos. The zebrafish embryos were exposed to the cannabinoid at 0.

Effects of Intrauterine Isoproterenol Administration on Ovarian Follicular Development in Cows.

Background: Isoproterenol (ISO) is a nonselective beta-adrenergic receptor agonist known for its vasodilatory effects. This experiment aims to investigate whether intrauterine ISO administration could alter vascular indices and follicular development in postpartum Holstein cows.

Objectives: The objectives are to evaluate the effects of intrauterine ISO administration on vascular changes and its impact on follicular development compared to placebo groups.

Adaptive leadership of doctors during COVID-19.

Purpose: This study aims to examine the adaptive leadership of doctors during COVID-19 to understand the leadership competencies required for adaptive events.

Design/methodology/approach: Phenomenology-based qualitative design was used. Data were collected from six doctors from the state of Kerala, India using semi-structured interviews.

Mental health during COVID-19 lockdown in India: Role of psychological capital and internal locus of control.

The Government of India implemented a nationwide lockdown from March 24, 2020 in response to the Coronavirus disease (COVID-19) outbreak. This study examines the effects of two positive psychological resources on the mental health of Indian citizens during the early days of the lockdown. The effects of psychological capital (PsyCap) and internal locus of control on psychological distress of people via affect balance were tested.

Understanding coronaphobia.

COVID-19 pandemic, in addition to being a global health emergency, has multiple socioeconomic and psychological ramifications. COVID-19 research and media reports have revealed a rise in fears related to contracting the virus. Though fear is a common psychological outcome during pandemics, the COVID-19 pandemic is a continuously evolving disease outbreak and has unique risk factors.

A malpractice: Stripping of the great saphenous vein without the division of the side-branches at the saphenofemoral junction.

Aim: To highlight the components of stripping operation of the great saphenous vein and to offer a proposal for guidelines.

Methods: 7789 admissions with venous insufficiency during the period, reaching seven and a half years were evaluated. Seventy- two admissions of nineteen patients were related to the recurrent symptoms due to previous incomplete stripping surgery.

The relationship between Raynaud's phenomenon and Helicobacter pylori.

Background: This study was aimed to reveal whether there is a relationship between Raynaud Phenomenon (RP) and Helicobacter Pylori (HP).

Material And Methods: Seventy-nine patients, who had been referred to outpatient clinic with Raynaud in the last 9 years were retrospectively screened. Of these, 29 patients with access to their data and who had HP screening tests were included in the study.

Replacement of the Native Mitral Valve Due to Endocarditis Caused by Stenotrophomonas Maltophilia.

We report a case of a 59-year-old female patient with vegetative native mitral valve endocarditis caused by Stenotrophomonas maltophilia (SM). She had hemodialysis-dependent chronic renal failure, but no immunosuppressive disease. Echocardiography showed mobile vegetation on her native mitral valve.

Anti-Inflammatory Effect of Rosa rugosa Flower Extract in Lipopolysaccharide-Stimulated RAW264.7 Macrophages.

Rosa rugosa Thunb, a deciduous shrub of the genus Rosa, has been widely used to treat stomach aches, diarrhoea, pain, and chronic inflammatorydisease in eastern Asia. In recent years, our research team has extensively studied the Rosa rugosa flowerextract, and specificallyundertook pharmacological experiments which have optimized the extraction process. Our methods have yielded a standard extract enriched in phenolic compounds, named PRE.

Bereavement, postdisaster trauma, and behavioral changes in tsunami survivors.

This study examined whether the death of family members intensifies the survivors' posttraumatic stress and behavioral changes. Data were collected by interviewing 416 adult survivors from nine habitations of the Nagapattinam district in the state of Tamil Nadu in India 14 months after the 2004 tsunami. Compared to those nonbereaved, bereaved survivors reported more posttraumatic stress disorder, depression, anxiety, negative affect, deteriorated mental health, adverse physical health symptoms, alcohol consumption, family conflicts, and fear.

A dilemma: prophylaxis for pulmonary embolism after surgical or invasive interventions for hemodialysis.

Aim: This study was designed to investigate if it needs to do prophylaxis for pulmonary embolism in the patients treated with different kinds of dialysis or not, and if it is, to find a proper method for prophylaxis.

Methods: Ten numbers of patients with central venous catheters (CVC group), 13 numbers of patients with arteriovenous fistula (AVF group) were enrolled in this study. Eleven patients treated with peritoneal dialysis (PD group) were utilized as a control group.

Early postoperative candida colonization in alimentary canal in patients undergoing open heart surgery.

Aim: To examine the frequency and factors predisposing to candidiasis in the digestive tract in the early postoperative period after open heart surgery.

Methods: One hundred patients undergoing open heart surgery were enrolled in this study. Patients were divided into 2 groups in regard to Candida spp.

The mechanical or electrical induction of medullary angiogenesis: will it improve sternal wound healing?

We induced angiogenesis in the tibial medulla and cortex of rabbits by electrical and mechanical stimulation, with the aim of future application to ischemic disease. Sixteen New Zealand rabbits were divided into 4 groups: in Group 1, a K wire was inserted into the medullary channel; in Group 2 a hole was drilled into the tibia; in Group 3, electrical stimulation was applied to the medullary channel; and in Group 4 (the control group), nothing was done. The interventions were applied during a 21-day period, after which all animals were evaluated scintigraphically and histopathologically.

Successful treatment of Buerger's Disease with intramedullary K-wire: the results of the first 11 extremities.

Objective: This study describes a new technique for treatment of Buerger's disease, developed to stimulate angiogenesis, using a Kirschner wire placed in the medullary canal of the tibia. The aim of the study was to evaluate clinical and radiological effects of this technique in patients where medical and surgical therapy had failed.

Material And Methods: Eleven extremities (six patients) with Buerger's disease were treated with the intramedullary Kirschner wire technique.

Induced angiogenesis with intramedullary direct current: experimental research.

The purpose of this study was to evaluate angiogenesis after the use of intramedullary direct electrical current in rabbit tibia. Thirty-two New Zealand rabbits were divided into four groups: group 1, false electrode group; group 2, hole group; group 3, control group; and group 4, intramedullary electrical stimulation group. One-half of the rabbits in each group were evaluated angiographically, pathologically, and scintigraphically on day 7, and the rest were evaluated on day 21.

Acute abdominal aorta embolism caused by rupture of a cardiac hydatid cyst.

We report a case of an abdominal aortic embolism due to rupture of a cardiac hydatid cyst. This report emphasizes the diagnostic, preventative, and treatment options for hydatid cyst embolism of abdominal aorta. Echocardiography should be routinely performed in all patients with hydatid disease for possible involvement of the heart.