Understanding Comprehensive Sexuality Education: A Worldwide Narrative Review.

Comprehensive sexuality education (CSE) is curriculum-based teaching and learning of various dimensions of sexuality. By equipping young people with accurate information on sexual and reproductive health, CSE promotes healthier populations and fosters a more informed workforce, contributing positively to national economies. Although known to have many benefits, CSE is not universally accepted or implemented.

Causes and risk factors for stillbirth in India: A systematic review protocol.

Objectives: Stillbirths, the tragic loss of a baby before or during delivery, presents a profound global health concern. Investigating the diverse causes and risk factors is essential to develop targeted interventions, enhance perinatal care, and reduce the incidence of this devastating outcome. The aim of this study was to identify the causes and possible risk factors of stillbirths in India.

A COMPREHENSIVE REVIEW ON EARLY DETECTION OF DRUSEN PATTERNS IN AGE-RELATED MACULAR DEGENERATION USING DEEP LEARNING MODELS.

Age-related Macular Degeneration (AMD) is a leading cause of visual impairment and blindness that affects the eye from the age of fifty-five and older. It impacts on the retina, the light-sensitive layer of the eye. In early AMD, yellowish deposits called drusen, form under the retina, which could result in distortion and gradual blurring of vision.

Successful Treatment Outcome of a Pediatric Malignant Germ Cell Tumor With an Extensive Cavo-atrial Tumor Thrombus Presenting as an Oncological Emergency.

Background: Pediatric germ cell tumor (GCT) with extensive cavo-atrial tumor thrombus presenting as an oncologic emergency is extremely rare.

Observation: A 13-month-old female child with sacrococcygeal GCT having inferior vena cava (IVC) and right atrial thrombus presenting with anasarca and respiratory distress is reported. Because of worsening symptoms post initiation of chemotherapy, tumor thrombus debulking from the right atrium and distal end of IVC was performed on day 9 on an emergency basis.

Carbon Monoxide in Healthcare Monitoring Balancing Potential and Challenges in Public Health Perspective: A Narrative Review.

Carbon monoxide (CO) has medicinal potential and harmful qualities. However, excessive exposure to CO can lead to severe organ failure. CO is exogenously and endogenously generated within the human body.

Severe corneal manifestations of graft-versus-host disease: Experience of a tertiary referral center.

Purpose: Graft-versus-host disease (GVHD) is a common complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). GVHD may affect several organs, including ocular manifestations, ranging from dry eye syndrome to sight-threatening corneal ulceration or perforation. Limited information is available about characteristics and treatments of ocular GVHD and its relation to general prognosis.

Revisit to Endolymphatic Duct Identification Using Middle Cranial Fossa Dural Plate: A Novel Technique.

Objectives: Surgical treatments for Ménière's disease differ in efficacy. Endolymphatic duct blockage (EDB) is favored for its minimal risk and ability to preserve hearing. One of the main challenges in the technique is the difficulty in accurately identifying the endolymphatic duct (ED).

Beverage Combination of Pomegranate Juice and Quinoa Extract Ameliorates Lipid Profile in Rat Study.

Effect of fruit and cereal grain-based beverage studies on the lipid profile are limited. Pomegranate fruit and quinoa grains are known for their abundance of polyphenols with several health beneficial effects. The present study was carried out to investigate the effects of oral administration of beverage containing pomegranate juice and quinoa seed extract in obese rats.

Sensorless vector-controlled induction motor drives: Boosting performance with Adaptive Neuro-Fuzzy Inference System integrated augmented Model Reference Adaptive System.

The Model Reference Adaptive System (MRAS) is effective for speed control in sensorless Induction Motor (IM) drives, particularly at zero and very low speeds. This study enhances MRAS's resilience and dynamic performance by integrating an Adaptive Neuro-Fuzzy Inference System (ANFIS) controller into sensorless vector-controlled IM drives. The research addresses challenges related to parameter uncertainties, load variations, and external disturbances through the combination of MRAS and ANFIS.

Fmoc-Pro-Phe-OMe dipeptide carbon sensor for simultaneous detection of chloramphenicol (CP) and furazolidone (FZ) toxic residues in food samples.

In this work, we fabricated the Fmoc-Pro-Phe-OMe modified carbon paste electrode (FPPO/MCPE) and used it for electrochemical detection of CP and FZ in a 0.1 M phosphate buffer solution (pH = 7). We characterized the Fmoc-Pro-Phe-OMe and applied it for the electrochemical detection of CP and FZ.

Exploring diabetes through the lens of AI and computer vision: Methods and future prospects.

Early diagnosis and timely initiation of treatment plans for diabetes are crucial for ensuring individuals' well-being. Emerging technologies like artificial intelligence (AI) and computer vision are highly regarded for their ability to enhance the accessibility of large datasets for dynamic training and deliver efficient real-time intelligent technologies and predictable models. The application of AI and computer vision techniques to enhance the analysis of clinical data is referred to as eHealth solutions that employ advanced approaches to aid medical applications.

A Case of Complex Deformity of Knee Corrected by Ilizarov Fixation in a Teenage Patient.

Introduction: After the spine, the knee is the second most common location for skeletal tuberculosis. An unusual complication of tuberculosis infection is triple knee deformity. The combination of knee flexion, posterolateral tibial subluxation, and external tibial rotation over femoral condyles manifests as a severe deformity.

Prevalence of hypothyroidism in older adults and its association with cognition: a cross-sectional study from a South Indian ageing urban cohort.

The study conducted on a South Indian urban cohort aimed to emphasize the prevalence and patterns of hypothyroidism and its association with cognition among individuals aged 45 years and above. A cross-sectional design was adopted, utilizing data from the Tata Longitudinal Study of Aging cohort, comprising 1201 non-demented participants in Bangalore, South India. The study contains detailed clinical assessments, including medical history, physical examination and cognitive tests such as the COGNITO battery, Hindi Mental State Examination and Addenbrooke's Cognition Examination III.

A Case of Kanamycin Self-Injection for Penile Augmentation and a Literature Review of Penile Foreign Body Injections.

Injection of various substances into the penis for augmentation is an uncommon and concerning practice that can have serious consequences, such as skin necrosis, ulcers, suboptimal cosmetic results, and persistent edema, often requiring extensive surgical repair. In this article, we present a rare case of penile self-injection with Kanamycin ointment. We describe the clinical course of the disease and the management framework that was followed.

Revisiting the Intratemporal Course of the Facial Nerve.

Introduction The facial nerve displays a lot of variations and anomalies in its course. Having sound knowledge about the surgical anatomy along with its intricacies is essential in mastoid surgeries. In this study, we have documented the angle of deviation of the mastoid segment of the facial nerve during its intratemporal course and the importance of this angle during mastoid surgeries.

Antibody-modified 2D MXene nanosheet probes for selective, picolevel detection of cancer biomarkers.

Cancer biomarkers are crucial indicators found in clinical samples, playing a key role in early detection, diagnosis, and treatment of cancer. Detecting these biomarkers with high sensitivity is essential for early diagnosis, especially in aggressive cancers like lung cancer, which is the leading cause of cancer-related deaths. Carcinoembryonic antigen (CEA) is a critical biomarker for lung cancer, and its detection aids in identifying the disease at an early stage.

VaxOptiML: leveraging machine learning for accurate prediction of MHC-I and II epitopes for optimized cancer immunotherapy.

Cancer immunotherapy hinges on accurate epitope prediction for advancing vaccine development. VaxOptiML (available at https://vaxoptiml.streamlit.

Twist of Fate: A Case Series on Intestinal Malrotation in Adult Patients.

Intestinal malrotation is a congenital anomaly characterized by rotational errors during the embryonic development of the midgut. Although it is mainly a pediatric diagnosis, some cases do present in adult life. In adults, the condition can present in various ways, with symptoms that may be acute, acute on chronic, chronic, or discovered incidentally.

Brain-scale theta band functional connectome as signature of slow breathing and breath-hold phases.

The study reported herein attempts to understand the neural mechanisms engaged in the conscious control of breathing and breath-hold. The variations in the electroencephalogram (EEG) based functional connectivity (FC) of the human brain have been investigated during attentive breathing at 2 cycles per minute (cpm). The study presents its novelty through three main aspects.

Perception of First-Year MBBS Students Toward Virtual Dissection in Learning Anatomy: A Comparative Study Between High and Low Academic Achievers.

Introduction Anatomy, as a crucial subject in the medical curriculum, demands continuous efforts to adopt innovative teaching methods to make it a student-friendly subject. One of the new educational technologies is the virtual anatomy dissection. This high-tech tool allows students to perform some hands-on manipulation of a digital cadaver through an electronic screen in the form of a table.

The influence of fascial manipulation on shoulder range of motion, pain, and function in individuals with chronic shoulder pain.

Background: A prevalent musculoskeletal condition that has a substantial socioeconomic impact and causes considerable morbidity is chronic shoulder pain (CSP). CSP may result from a dysfunction of the upper quarter region's (UQR) myofascial continuum (MC), which is connected by deep fascia. Fascial Manipulation® (FM), proposed by Luigi Stecco, involves deep kneading performed at specific points on the deep fascia.

Power yoga induced acute para-spinal compartment syndrome: a case report and review of literature.

Purpose: Acute Paraspinal compartment syndrome (PCS) is a very rare clinical condition resulting from high pressures within the erector spinae muscle compartment due to intense edema of the erector spinae muscles and can be associated with rhabdomyolysis and renal injury. Though several causes have been identified, PCS caused by power yoga has not been reported. Power yoga is a form of fast and vigorous yoga, and involves intense flexion-extension of the spine and other parts of the body in a repetitive manner.

"Development, optimization, and characterization of Eudragit-based nanoparticles for Dasatinib delivery".

This study focused on developing and evaluating dasatinib-loaded nanoparticles (DST-NPs) using Eudragit L100 as a polymer matrix for enhanced breast cancer treatment. The optimized formulation exhibited a particle size of 202.1 ± 5.