Publications by authors named "O von Richter"

Background: Atrial fibrillation detected after stroke (AFDAS) is considered to be a distinct entity influenced by cardiogenic and neurogenic factors. We hypothesized that patients with AFDAS have larger stroke lesions than patients without atrial fibrillation (AF) and with known AF (KAF).

Methods And Results: Consecutive patients with magnetic resonance imaging-confirmed acute ischemic stroke admitted to a university hospital between October 2020 and January 2023 were prospectively registered.

View Article and Find Full Text PDF

By mimicking the neurons and synapses of the human brain and employing spiking neural networks on neuromorphic chips, neuromorphic computing offers a promising energy-efficient machine intelligence. How to borrow high-level brain dynamic mechanisms to help neuromorphic computing achieve energy advantages is a fundamental issue. This work presents an application-oriented algorithm-software-hardware co-designed neuromorphic system for this issue.

View Article and Find Full Text PDF

Aim: The rat lungworm, Angiostrongylus cantonensis, has recently been found in the city of Valencia, parasitizing rats, Rattus norvegicus and Rattus rattus, its natural definitive hosts. This is the first finding of this zoonotic nematode in continental Europe. After informing local and national health authorities, the collection of local terrestrial snails took place with the aim of elucidating their potential role as intermediate hosts of A.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigated the antidrug antibody (ADA) signal-to-noise (S/N) ratio as a new way to measure immune responses in healthy individuals after taking a single dose of the adalimumab biosimilar, GP2017.
  • Validated bioanalytical methods were used to analyze ADA S/N ratios and titers, showing a strong correlation between the two measures.
  • The ADA S/N ratio proved to be more sensitive and better correlated with the pharmacokinetics of the drug, indicating it could more effectively assess the immune response compared to traditional ADA titers.
View Article and Find Full Text PDF

This paper shows how biological population dynamic models in the form of coupled reaction-diffusion equations with nonlinear reaction terms can be applied to heterogeneous landscapes. The presented systems of coupled partial differential equations (PDEs) combine the dispersal of disease-vector mosquitoes and the spread of the disease in a human population. Realistic biological dispersal behavior is taken into account by applying chemotaxis terms for the attraction to the human host and the attraction of suitable breeding sites.

View Article and Find Full Text PDF