Publications by authors named "O de Divitiis"

Head and neck squamous cell carcinoma (HNSCC) can, in rare instances, metastasize to the CNS, which is often associated with a poor prognosis. We present the case of a 65-year-old male with a history of HNSCC who developed two enhancing brain lesions: one in the right parietal region and another in the right insular region. Initially, the patient was managed with CyberKnife radiosurgery targeting both lesions.

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Article Synopsis
  • The study examines the effectiveness of anterior vs. posterolateral surgical approaches for treating thoracic disc herniation (TDH) and highlights variations in technique across different institutions.
  • A systematic review and meta-analysis of existing literature revealed that the posterolateral approach is linked to fewer complications, less blood loss, and shorter hospital stays compared to the anterior approach.
  • Results indicate that the posterolateral technique not only promotes neurological recovery but also achieves higher rates of complete hernia resection, suggesting it may be a safer and more effective option for TDH surgery.
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Background: Biphenotypic sinonasal sarcoma (BSNS) is a low-grade tumor of the sinonasal tract with frequent extension to the orbit and skull base. Due to its rare incidence and recent histopathological and molecular characterization, little data are available in regard to its natural history, treatment and surveillance protocol.

Methods: A comprehensive literature review in Embase online electronic databases on BSNS was made.

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  • * It analyzed data from 98 patients treated between 2011 and 2023, comparing outcomes of various surgical techniques like laminectomy, thoracoscopic surgery, and open thoracotomy.
  • * Key findings suggest combined surgical approaches are better for certain types of TSs, and factors like patient sex, tumor location, and surgical resection extent play crucial roles in recurrence rates.
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  • - Biphenotypic sinonasal sarcoma is a rare, low-grade tumor found in the sinonasal tract, known for its aggressive growth and tendency to spread to surrounding areas like the orbit and skull base.
  • - A comprehensive study reviewed 31 cases, highlighting that it primarily affects middle-aged women, with surgery being the main treatment method, resulting in a gross total resection in two-thirds of the patients.
  • - The endoscopic endonasal approach was the most common surgical method, with a local recurrence rate of 19.3% and a low mortality rate, indicating that effective management of the tumor primarily relies on surgery.
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