The retreat of Arctic sea ice has opened new maritime routes, offering faster shipping opportunities; however, these routes present significant navigational challenges due to the harsh ice conditions. To address these challenges, this paper proposes a deep learning-based Arctic ice risk management architecture with multiple modules, including ice classification, risk assessment, ice floe tracking, and ice load calculations. A comprehensive dataset of 15,000 ice images was created using public sources and contributions from the Canadian Coast Guard, and it was used to support the development and evaluation of the system.
View Article and Find Full Text PDFCarrageenans have demonstrated enhanced antitumor activity upon depolymerization into disaccharides. However, the pharmacological viability of these disaccharides and their mechanisms of antitumor action remains to be fully elucidated. This study aimed to employ computational tools to investigate the pharmacological properties and molecular targets pertinent to cancer of the disaccharides derived from the primary carrageenans.
View Article and Find Full Text PDFArch Pharm (Weinheim)
January 2025
The Amazon rainforest is renowned for its biodiversity and as a reservoir of edible and medicinal plants. The phytochemicals in murici and taperebá fruits serve as natural antioxidants, contributing to cultural preservation, ecosystem protection, and economic opportunities. However, limited scientific research on their composition and health benefits hinders their recognition as functional foods.
View Article and Find Full Text PDFUnlabelled: Endometriosis is a chronic disease characterized by the growth of the endometrium outside the uterine cavity. In response to estradiol, this tissue begins to proliferate and grow, forming lesions and nodules, which can invade the tissues, causing pelvic pain and infertility. The most widely used pharmacological treatment is progesterone, which manages to reduce symptoms, but approximately one-third of patients develop resistance to treatment.
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