Publications by authors named "O Z Fass"
Reflux, eosinophilic esophagitis, and celiac disease - the blurred lines.
Curr Opin Otolaryngol Head Neck Surg
December 2024
Article Synopsis
- Gastroesophageal reflux disease (GERD) is a common cause of dysphagia, while eosinophilic esophagitis (EoE) and celiac disease are rarer but often overlooked, making diagnosis challenging due to symptom overlap.
- Recent research has improved understanding of how dysphagia manifests in these conditions, emphasizing the importance of tests like upper endoscopy and biopsies, while also introducing new diagnostic methods.
- Properly distinguishing between GERD, EoE, and celiac disease is essential for effective treatment; EoE should be suspected in GERD patients who don't respond to standard therapy, and celiac disease should be considered if dysphagia occurs with
Background: Understanding the relationship between distal contractile integral (DCI) and mean nocturnal baseline impedance (MNBI) could shed light on new diagnostic and treatment strategies, specifically concerning nocturnal reflux. This study aimed to assess this relationship to enhance our comprehension of the interplay between esophageal contractility and mucosal permeability.
Methods: We identified adult patients who had high resolution esophageal manometry and pH-impedance tests performed within a 30-day period between December 2018 and March 2022.
Artificial Intelligence Tools for Improving Manometric Diagnosis of Esophageal Dysmotility.
Curr Gastroenterol Rep
April 2024
Purpose Of Review: Artificial intelligence (AI) is a broad term that pertains to a computer's ability to mimic and sometimes surpass human intelligence in interpretation of large datasets. The adoption of AI in gastrointestinal motility has been slower compared to other areas such as polyp detection and interpretation of histopathology.
Recent Findings: Within esophageal physiologic testing, AI can automate interpretation of image-based tests, especially high resolution manometry (HRM) and functional luminal imaging probe (FLIP) studies.
Background: Integrated relaxation pressure (IRP) calculation depends on the selection of a single gastric reference sensor. Variable gastric pressure readings due to sensor selection can lead to diagnostic uncertainty. This study aimed to examine the effect of gastric reference sensor selection on IRP measurement and diagnosis.
View Article and Find Full Text PDFBackground/aims: Presently, there is paucity of information about clinical predictors, especially esophageal motor abnormalities, for long segment Barrett's esophagus (LSBE) as compared with short segment Barrett's esophagus (SSBE). The aims of this study are to compare the frequency of esophageal function abnormalities between patients with LSBE and those with SSBE and to determine their clinical predictors.
Methods: This was a multicenter cohort study that included all patients with a diagnosis of BE who underwent high-resolution esophageal manometry.