[The lack of the CpNpG methylation at the 5'-terminal region of the human calcitonin gene in norm and in leukemia [].

The inner cytosine methylation was analyzed in the CCWGG sequences of the 5'-terminal region of the human calcitonin gene from peripheral blood and bone marrow cells in various forms of leukemia. Since these sequences remain nonmethylated both in norm and in various leukemia forms, the CpG dinucleotide hypermethylation of the 5'-terminus of the human calcitonin gene, characteristic for the development of leukemias, does not spread over adjacent CpNpG sequences.

[Comparative informative value of chromosome aberrations and sister chromatid exchanges in the evaluation of metals in the environment].

Simultaneous recording of the frequency of chromosomal aberrations and sister chromatid exchanges supplements data on the nature of genetic disorders in the sanitary and toxicological assessment of metals polluting the environment. A obvious threshold of genetic effects of metals was not revealed in the context of chromosomal aberrations and sister chromatid exchanges. Methods for detecting the genotoxicity of metals await further search.

[The treatment of patients with chronic cerebral circulatory failure by using laser puncture and the microclimate of the biotron].

A mode is proposed of treatment of chronic cerebrovascular disorders, such as initial manifestations of cerebral blood supply insufficiency (IMBSI) and dyscirculatory encephalopathy (DE) stage I-II in hypertensive disease, involving the use of laser puncture and microclimate of biotron. All patients (n = 162) were exposed to laser puncture (10-12 procedures). Laser puncture treatments were devised according to classical approaches of reflexotherapy, using determinants of electropuncture diagnostic method by Riodoraku.