[Optimization of early postoperative period in intestinal resection surgery for acute intestinal obstruction complicated by peritonitis].

Objective: To establish the effectiveness of complex therapy with Remaxol in optimizing the early postoperative period and increasing the reparative ability of intestinal tissues in acute intestinal obstruction complicated by peritonitis.

Material And Methods: We analyzed treatment outcomes in 37 patients with acute intestinal obstruction complicated by peritonitis. The control group included 19 patients who underwent standard therapeutic measures after resolving intestinal obstruction and resection of small or large intestine.

[Systemic inflammatory response syndrome in pancreatic necrosis: triggers and organ damage].

Objective: To determine the main trigger mechanisms of multiple organ failure in acute severe pancreatitis.

Material And Methods: An experimental study included 26 dogs with pancreatic necrosis. We assessed homeostasis disorders and functional changes in the pancreas, bowel, liver, kidneys, lungs and heart.

[Remaxol in Correction of Functional Hepatic Failure in Patients with Acute Biliary Pancreatitis].

The effcacy of Remaxol was studied in the treatment of patients with acute biliary pancreatitis under clinical and laboratory con- ditions by the recommended indices, as well as by the markers of endogenous intoxication, the intensity of lipid peroxidation, activity of some enzymes and indicators of hypoxia. The use of Remaxol in the treatment of acute biliary pancreatitis was highly resultant in correction (prevention of progression) of the functional hepatic failure and homeostatic disorders as a whole. It was demonstrated that the hepatoprotective effect of the drug was based on its ability to reduce oxidative stress, to inhibit excessive phospholipase activity and to alleviate the signs of general hypoxia.

[The possibilities of gastroduodenal anastomosis reliability rising].

An experimentally-clinical assessment of reparative regeneration collagenation of gastroduodenal anastomosis was made. The anastomoses were formed by different ways: the inverted twin-row (classical) and everting one-row anastomosis. It was stated, that tissues repair on suture-line of the everting anastomosis took place faster and better (on a type of primary intention with wound epithelization on 3-5 days).