Unlabelled: was to determine the molecular genetic prognostic criteria for the severity of the course pneumonia based on the analysis of the association of genetic polymorphism in toll-like receptors with the severity of NETosis.
Materials And Methods: The study included 38 patients with the main diagnosis of community-acquired pneumonia with a severe course. All the patients underwent standard clinical laboratory examinations, computed tomography of the thoracic organs, microbiological examination of blood and tracheobronchial aspirate.
The subjects of the study were 64 patients with coronary heart disease, and 38 healthy individuals. In order to evaluate the degree of endothelial dysfunction (ED) reactive hyperemia test was performed; the degree of the relative increase of the brachial artery diameter, and the level of desquamated endothelial cells circulating in blood (CEC) were used as criteria of this dysfunction. Only in 6.
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