Biotin-Thiamine-Responsive Basal Ganglia Disease: A Case Report.

Introduction: Biotin-thiamine responsive basal ganglia disease (BTBGD) is a rare autosomal recessive neurometabolic disorder characterized by diverse and variable phenotypic features, which can make diagnosis challenging. However, prompt treatment with thiamine and biotin can effectively manage the condition. Diagnosis relies on the identification of biallelic pathogenic variants in the gene.

Selenium modulates bisphenol A-induced intestinal apoptosis, oxidative stress and autophagy in rats: A biochemical, histological and immunohistochemical study.

Bisphenol A (BPA) is a hazardous endocrine disruptor released into the environment during the production of certain plastics used for covering of food and beverage cans. In this work, we examined the protective benefits of selenium (Se) against intestinal damage induced by BPA in male rats. Rats were distributed randomly into four groups.

Ferulic acid mitigated rotenone toxicity -Evoked Parkinson in rat model by featuring apoptosis, oxidative stress, and neuroinflammation signaling.

Over time, Parkinson disease (PD) develops as a neurological illness. The goal of this study was to see whether ferulic acid has any neuroprotective benefits on the cerebellum of rats that have Parkinson's disease brought on by rotenone poisoning. A total of twenty-four male albino rats, in good condition, weighed between 200 and 250 g and nine to ten weeks old, were employed in the investigation.

Awake lumbar spine surgery performed under spinal versus conventional anesthesia.

Background: Lumbar spine surgery for discectomy or laminectomy is mostly performed under general anesthesia (GA). Here, we explored whether, in a series of 84 patients, better peri-operative outcomes and lower complication rates could be achieved for those undergoing diskectomy/laminectomy under spinal anesthesia (SA) versus GA.

Methods: From 2022 to 2023, 84 patients were randomly assigned to undergo lumbar discectomy/laminectomy for stenosis under SA: 42 patients versus GAGA: 42 patients.