Functional and antigenic antithrombin III values in plasma and serum from 115 regular blood donors and antithrombin III in prediction of postoperative thrombosis.

Antithrombin III (AT-III) was determined functionally using chromogenic substrate (S-2238) and immunologically using radial immunodiffusion (RID) in plasma and serum from 115 blood donors. There was a decrease in functional activity by 43.5% and in antigen concentration by 18.

An attempt at predicting postoperative deep vein thrombosis by preoperative coagulation studies in patients undergoing total hip replacement.

Preoperative levels of fibrinogen, factors V, VII, VIII and antithrombin III were measured in 25 consecutive patients undergoing total hip replacement. Deep vein thrombosis (D.V.

Factor VIII (AHG) levels in 1016 regular blood donors. The effects of age, sex, and ABO blood groups.

Factor VIII (AHG) activity was assayed in the plasma specimens from 1016 regular and controlled blood donors. Age and ABO blood groups had highly significant effects on factor VIII concentrations, whereas the effect of sex was not significant. The median in the donors of blood group O rose from 87% at the age of 20 to 119% at the age of 60 years, and the median in blood groups A and B+AB of corresponding ages rose from 108 to 147%.

Factor V (proaccelerin) concentration in 1016 blood donors. The effects of age, sex, and ABO blood groups.

Factor V (proaccelerin) concentration was measured in the plasma of 1016 regular and controlled blood donors. Age had a highly significant effect on factor V concentration. The median rose from 99 per cent at the age of 20 to 123 at the age of 60 years.