Publications by authors named "O Watanabe"
Article Synopsis
- Immunofluorescence techniques for detecting HCoV-OC43 in nasopharyngeal swab specimens have not been developed before this study.
- A human rectal adenocarcinoma cell line (HRT-18) was used to analyze specimens from patients, with positive staining in cells for HCoV-OC43 found in nine out of eleven cases where RNA was detected.
- The study suggests that immunofluorescence staining with human serum can successfully identify replicating HCoV-OC43 in specimens, and potentially other viruses, indicating this method could be useful for broader viral detection.
Objective: Patients with hematopoietic malignancies (HM) are often immunocompromised and, therefore, susceptible to developing invasive fungal infections, including pulmonary mycosis. Surgical resection is indicated for localized pulmonary mycosis refractory to antifungal agents. This study investigated the feasibility and outcomes of minimally invasive surgery for pulmonary mycosis patients complicated with HM.
View Article and Find Full Text PDFHuman parainfluenza viruses (hPIVs) are causative agents of upper and lower respiratory tract infections and they have four serotypes. The virion surface displays hemagglutinin-neuraminidase (HN), having hemagglutinating (HA) and neuraminidase (NA) activities in a single molecule. The HA activity binds the virion to sialic acid on the viral receptor on host cells and the NA releases the progeny viruses from the cell surface.
View Article and Find Full Text PDFOur previous findings indicated that many respiratory syncytial virus (RSV) isolates are unstable at 4 °C compared to 20 °C. Some of the strains completely lose infectivity after 24 h at 4 °C. This study analyzed the inactivation process at 4 °C using a representative strain, RSV/Sendai/851/13.
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