Magnetic resonance imaging of the normal pituitary gland using ultrashort TE (UTE) pulse sequences (REV 1.0).

Introduction: The purpose of this study was to examine the normal pituitary gland in male subjects with ultrashort echo time (TE) pulse sequences, describe its appearance and measure its signal intensity before and after contrast enhancement.

Methods: Eleven male volunteers (mean age 57.1 years; range 36-81 years) were examined with a fat-suppressed ultrashort TE (=0.

Effects of maternal and long-term postnatal protein malnutrition on brain size and composition in rhesus monkeys.

Rhesus monkeys consumed purified diets that supplied either low or adequate levels of protein (3.8 vs. 13.

Metabolism of native and acetylated low density lipoproteins in squirrel monkeys with emphasis on aortas with varying severities of atherosclerosis.

We studied the clearance of 131I-labeled native low density lipoproteins (LDL) and 125I-acetyl LDL from the blood of hypercholesterolemic and atherosclerotic squirrel monkeys which had been fed a semipurified diet supplemented with cholesterol for 3 years and from control monkeys which had been fed the same diet without cholesterol. In agreement with previous observations in other species, acetyl LDL left the circulation much more rapidly than native LDL. The cholesterol supplemented monkeys removed native 131I-LDL to the liver, the major site of clearance of both LDL forms, more slowly than controls.

Different susceptibilities to the formation of cholesterol gallstones in mice.

In the search for an animal model of genetic determinants of cholesterol cholelithiasis, we found strain, gender and individual differences in mice. Male black (C57BL6J) mice had a 50% incidence of cholesterol gallstones after they consumed lithogenic food similar to that used by Tepperman et al. for 2 weeks, whereas similarly treated male agouti (CBA/J) mice and females of both strains were free of gallstones.

Metabolism of [125I]tyramine cellobiose-labeled low density lipoproteins in squirrel monkeys.

Low density lipoproteins labeled with [125I]tyramine cellobiose ([125I]TC-LDL) were removed from the circulation of squirrel monkeys at a similar but slightly slower rate than LDLs labeled with 125I, [125I]hydroxyphenyl propionic acid, or [3H]leucine. After the simultaneous injection of [125I]TC-LDL and [131I]LDL labeled with 131ICl, the 125I was also removed at a slightly slower rate than 131I. Most of the radioactivity was retained in tissues and not excreted during the 24 h after injection of [125I]TC-LDL.