Publications by authors named "O Vicent"

Article Synopsis
  • Direct oral anticoagulants (DOAC) can cause severe bleeding that is hard to detect using standard tests, leading to urgent recognition and management once a patient is admitted to the hospital.
  • New point-of-care viscoelastic testing (VET) methods like the Russell viper venom factor V test allow for quicker and more accurate measurement of DOAC levels, which is crucial during severe bleeding emergencies.
  • The study demonstrates the effectiveness of using RVV-clotting time to assess the reversal of direct FXa inhibitors after administering andexanet alfa, highlighting the need for reliable tests to monitor treatment outcomes in these critical situations.
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Small, portable hand-held ultrasound devices nowadays enable a widespread use of prehospital point-of-care ultrasound (pPOCUS), which has so far only been used hesitantly, especially in ground-based emergency services. Many critical or even life-threatening conditions or internal injuries can often be better diagnosed or ruled out using pPOCUS, which can enable faster and more suitable goal-directed treatment and hospital transport. This article critically discusses relevant data, clinical benefits, limitations and challenges to be overcome when using pPOCUS for the most important life-threatening situations and aims to call for intensifying training and the extensive use of pPOCUS.

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Background: Despite improving the management of proximal femur fractures (PFF) with legal requirements of timing the surgery within 24 h, mortality rates in these patients remain still high. The objective of our study was to analyze potential cofactors which might influence the mortality rate within 90 days after surgery in PFF to avoid adverse events, loss of quality of life and high rates of mortality.

Methods: In this retrospective, single-center study all patients with PFF aged 65 years and older were included.

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Bleeding events in patients under direct oral anticoagulation (DOAC) can be life-threating but are commonly not related to drug overdose. However, a relevant DOAC plasma concentration impairs the hemostasis and should therefore be ruled out immediately after hospital admission. The effect of DOAC is typically not visible in standard coagulation tests such as activated partial thrombin time or thromboplastin time.

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Background: SARS-CoV-2 infections are suspected to trigger the coagulation system through various pathways leading to a high incidence of thromboembolic complications, hypercoagulation and impaired fibrinolytic capacity were previously identified as potentially mechanisms. A reliable diagnostic tool for detecting both is still under discussion. This retrospective study is aimed to examine the prognostic relevance of early viscoelastic testing compared to conventional laboratory tests in COVID-19 patients with acute respiratory distress syndrome (ARDS).

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