Publications by authors named "O Vernet"
Article Synopsis
- - The study analyzed brain dynamics in 10 individuals with pharmacoresistant focal epilepsy and 30 healthy controls using resting-state functional MRI, focusing on how seizures start and spread.
- - Findings revealed significant changes in global brain connectivity, with increased integration and flexibility, and specific regions showing paradoxical decreases in ignition within the seizure onset zone.
- - The results contribute to a better understanding of epilepsy mechanisms and may help in creating diagnostic tools and therapies for seizure management.
Focal epilepsy can be conceptualized as a network disorder, and the functional epileptic network can be described as a complex system of multiple brain areas that interact dynamically to generate epileptic activity. However, we still do not fully understand the functional architecture of epileptic networks. We studied a cohort of 21 patients with extratemporal focal epilepsy.
View Article and Find Full Text PDFPurpose: The aim of this study was to apply sequential analysis of electroencephalography-functional magnetic resonance imaging (EEG-fMRI) data to study the cortical substrates related to the generation of the interictal epileptiform activity (IEA) in patients with pharmacoresistant extratemporal epilepsy.
Methods: We analyzed fMRI data from 21 children, adolescents, and young adults patients who showed frequent bursts or runs of spikes on EEG, by using the sequential analysis method. We contrasted consecutive fixed-width blocks of 10 s to obtain the relative variations in cerebral activity along the entire fMRI runs.
Purpose: We assessed the correlation between urodynamic score and presence of symptoms in children with lipomyelomeningocele, and the usefulness of this measure in monitoring these children.
Materials And Methods: We prospectively evaluated 29 patients 1 month to 13 years old (mean 1.9 years) with lipomyelomeningocele from 1995 to 2010.