Publications by authors named "O V Zaytseva"

Objective: Aim: The aim of the study was to reveal the peculiarities of reparative osteogenesis in experimental lower jaw defect under the conditions of hydroxyapatite-containing osteotropic material application and electrical stimulation.

Patients And Methods: Materials and Methods: An experiment was conducted on 48 mature male rats of the WAG population. All animals were divided into 4 groups (12 animals in each group).

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Objective: The aim was to reveal the morphological features of the lungs in post-COVID-19 syndrome.

Patients And Methods: Materials and methods: The material of the study was autopsy material - fragments of the lung tissue from 96 deceased (59 men and 37 women). During the lifetime, all patients had in anamnesis COVID-19 of varying severity, and after the treatment of this infection, they had various manifestations of respiratory failure until death.

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Article Synopsis
  • A bidirectional Mendelian randomization study was conducted to analyze how six personality traits (including anxiety and neuroticism) impact back pain, and how back pain influences these traits.
  • Genetic data from major studies of individuals with European ancestry were used to perform sophisticated statistical analyses for this investigation.
  • Results indicated a strong causal relationship between neuroticism and back pain, suggesting that managing neuroticism could be beneficial for patients suffering from back pain.
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Background Context: Cardiovascular risk factors (hypertension, dyslipidemia, and type II diabetes) have been proposed as risk factors for back pain. However, few longitudinal studies have found significant associations between cardiovascular risk factors and back pain, and these may be explained by confounding or reverse causation.

Purpose: To examine potential causal effects of cardiovascular risk factors on back pain, and vice versa.

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Article Synopsis
  • The FUBP1 protein, known for binding single-stranded DNA, has a role in activating MYC transcription, while its counterpart Psi in Drosophila binds RNA to regulate splicing and promote growth.
  • Psi not only activates MYC for cell growth but also directly binds stg to synchronize growth with cell division, with its knockdown leading to reduced division in wing imaginal discs.
  • Psi also represses the growth inhibitor gene tolkin, and manipulation of tok levels affects cell proliferation, demonstrating that Psi manages growth by activating pro-proliferative genes and repressing inhibitors.
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