Cerium-Containing N-Acetyl-6-Aminohexanoic Acid Formulation Accelerates Wound Reparation in Diabetic Animals.

Background: The main goal of our study was to explore the wound-healing property of a novel cerium-containing N-acethyl-6-aminohexanoate acid compound and determine key molecular targets of the compound mode of action in diabetic animals.

Methods: Cerium N-acetyl-6-aminohexanoate (laboratory name LHT-8-17) as a 10 mg/mL aquatic spray was used as wound experimental topical therapy. LHT-8-17 toxicity was assessed in human skin epidermal cell culture using (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.

[Ways of indication rise for operation in elderly and senile aged patients with stomach cancer].

An article presents an analysis of treatment of 113 patients (aged from 60 to 91 years old) with stomach cancer. On this basis, an algorithm of examination of given age group was developed. Preoperative diagnostics wasn't directed only to an establishment of prevalence, a stage of main process.

[Possibilities of surgery optimization for esophageal carcinoma in age-related aspect].

The article presents an experience of treatment of 180 patients with esophageal carcinoma. A resection of the esophagus with the gastric graft plasty was performed using original methods in 163 patients. There were 74 patients at a mature age and 89 patients at an elderly and senile age.

[The role of tension plasty in surgical treatment of vast and gigantic postoperative ventral hernias].

An experience with treatment of 106 patients with vast and gigantic postoperative ventral hernias is summarized who were subjected to tension plasty of the abdominal wall with supraapo-neurotic fixation of a synthetic reticulate prosthesis. Monitoring of the mean calculated pressure in the pulmonary artery was made in 84 (79%) patients, in 34 (32%)--the intra-abdominal pressure. Local complications were registered in 13 (12.