[The effect of hydrogen peroxide and hypochlorite on brain Na,K-ATPase activity].

Brain Na,K-ATPase is subjected to direct modifying influence of the hypochlorite anion and hydrogen peroxide resulting in irreversible inactivation of the enzyme. The K0.5 values for these compounds are 20-40 microM and 1 mM, respectively.

[Oxaloacetate-dependent calcium transport in rat liver mitochondria].

The effect of oxaloacetate on Ca2+ transport in isolated rat liver mitochondria has been studied. Under aerobic conditions in the presence of oxaloacetate mitochondria accumulate Ca2+ in a ruthenium red- and uncoupler-sensitive way. Oxaloacetate catalyzes also the slow (5 nM Ca2+/min/mg protein) uptake of limited amounts of calcium by the mitochondria in the presence of respiratory chain and ATPase inhibitors.

[A comparison of the antioxidative activity of carnosine by using chemical and biological models].

The difference in the efficiency of carnosine as an antioxidant was found to be explained both by the source of carnosine and the specificity of models used to achieve visualization. Commercial carnosine samples were contaminated with compound (s) absorbing at 255-332 nm. At the same time they possessed better antioxidant activity in the models with Fe2-induced peroxidation process.