Comparative evaluation of purine dysmetabolism in gastric and pulmonary adenocarcinomas.

Aim: To study the state of purine metabolism in gastric (GAC) and pulmonary (PAC) adenocarcinomas and to assess its clinical and pathogenetic significance.

Patients And Methods: One hundred and six male patients were examined, among whom were 63 subjects aged 34 to 79 suffering from GAC, and 43 subjects aged 24 to 76 suffering from PAC. In GAC, the ratio of the pyloric, corporeal and antral localization of the tumor and variant of overall gastric lesion accounted to 24:5:1:1; and that of the central and peripheral PAC was 2:1.

MARKERS OF THE LUNG CANCER COMPLICATIONS.

Lung cancer (LC) occupies the first place in the structure of cancer morbidity and its prevalence is growing every year. Prognosis of LC course and its complications is a topical task of modern oncology. Further improvement of laboratory prognostic criteria for LC diagnosis and reliable markers of complications of the disease are necessary.

Paraneoplastic syndrome in lung cancer.

Aim: To study the nature of different variants of paraneoplastic syndrome (PNPS) in lung cancer, taking into account the features of the tumorous process and the complications of radiochemotherapy.

Patients And Methods: We performed an analysis of the data of 1,669 patients with lung cancer aged between 24 and 87 years, among whom there were 89% of men and 11% of women. The ratio of small cell and non-small-cell histological variants of the lung cancer was 1: 4, IB, IIA, IIB, IIIA, IIIB and IV stages of cancer - 1:2:6:58:43:57.

Bone tissue lesion in oncological disease (literature review and own research data).

A review of the current literature and our own researches data are presented. Malignant tumors all over the world cause a huge medical social and economic damage, being one of the main causes of people death in all countries. Involving bones in the pathological process occurs in every other patient with cancer.

The state of bone metabolism in lung cancer patients.

Unlabelled: In recent years, we have discussed the correlation of malignant tumor process with the development of osteoporosis, which can be exacerbated by ongoing chemotherapy and radiation therapy. The aim of the work was to assess the status of bone metabolism in 32 untreated patients with lung cancer without metastasis.

Materials And Methods: Patients underwent dual-energy X-ray osteodensitometry of proximal part of femoral bone.