Publications by authors named "O V Stukalova"

Article Synopsis
  • Barth syndrome is a rare genetic disorder linked to abnormal cardiolipin metabolism, leading to high mortality rates, especially from heart issues and infections within 5 years of being diagnosed.
  • The article presents a clinical case of an adult patient, highlighting the disease's progression from hypertrophic cardiomyopathy to hypokinetic cardiomyopathy as the patient aged.
  • It emphasizes the challenges in finding effective treatment options for Barth syndrome due to a lack of definitive guidelines and targeted therapies in clinical practice.
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The article presents a clinical case of heart failure associated with the anthracycline-containing antitumor therapy in a breast cancer patient with an initially low risk of developing cardiovascular complications.

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Aim: To evaluate the effect of Sacubitril/Valsartan (S/V) on the functional status, systolic and diastolic function of the left ventricle (LV), tolerability of therapy and to determine predictors of its effectiveness in patients with cancer therapy-related heart failure (СTRHF).

Materials And Methods: Forty patients 58 [46; 65.5] years of age with HF associated with anthracycline-containing cancer therapy were enrolled.

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Aim      To evaluate a possibility of using radiofrequency catheter ablation guided by intracardiac echocardiography (ICE), its efficacy and safety for treatment of ventricular tachycardia (VT) of various etiology.Material and methods  Catheter intervention was performed for 20 enrolled patients with symptomatic VT. Ablation procedures were guided by a 3D electroanatomical mapping system and ICE.

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Currently, the world is constantly increasing the number of people with obesity. As was shown by the Framingham study, obesity is a risk factor for many cardiovascular diseases. The effect of obesity on the structure and function of the heart is manifested in the form of cardiac remodeling, the effect on energy metabolism in the heart and infiltration of both myocardium with lipids, and an increase in the accumulation of adipose tissue in the pericardium, imbalance of adipokines and activation of inflammatory markers.

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