Publications by authors named "O V Stoianova"

Content of amino acids in the blood serum using ion-exchange chromatography and a quantitative crystalloscopic "closed drop" method was measured in 105 patients with multiple sclerosis of different severity. The relation between the dynamics of content of glutamic, asparagine acids and glycine and the disease severity was determined. The highest level of glutamic acid was found in the patients with severe disease course.

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Thirteen antibiotics of red, rose, yellow and violet color, which are synthesized by the soil Streptomycetes on the complete corn-bean medium have been isolated and purified by means of thin layer chromatography. Antibiotic activity of the obtained compounds has been determined against a series of gram-positive and gram-negative microorganisms, and also yeasts. The maxima of absorption of antibiotics in visible and UV-light were established.

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Glucoamylase from Aspergillus awamori 466 was immobilized on various supports. The enzyme sorption depends on its amount, the type of support, and immobilization conditions. The kinetics of acidic inactivation of the native and immobilized enzyme was studied.

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Investigation of the blood sera of patients with fresh syphilis forms before, immediately after, and in 6-18 months after treatment has confirmed a high sensitivity of the serologic tests for syphilis used in this country. The results of dynamic serologic monitoring of patients have demonstrated high efficacy of the therapeutic method used.

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