[The parents evaluation of accessibility of out-patient ophthalmologic care in Chelyabinsk].

Every year number of eye diseases among children and adolescents is steadily increasing. The most possible causes of this process are sedentary life-style, computerization of society and school curriculum characteristics. The survey of 209 parents of children and adolescents was organized and carried out.

[Effectiveness of 3-hydroxypyridine and succinic acid derivatives in complex treatment of primary open-angle glaucoma].

Prospective, placebo-controlled, single-blind, randomized clinical investigation of the influence of domestic 3-hydroxypyridine and succinic acid derivatives (emoxipin, reamberin, mexidol) on the effectiveness of a complex treatment of primary open-angle glaucoma (POAG) has been performed in a group of patients. It is established that intravenous infusion of 3-hydroxypyridine derivatives (emoxipin and mexidol) for two weeks, beginning 14 days after the start of POAG treatment, produced a retinoprotective action, with three months postponed changes in the central retinal artery (CRA) blood velocity. The retinoprotective effect of emoxipin (single dose, 150 mg) was manifested by reduction in the horizontal size of blind spot in two weeks, with the subsequent reduction of the CRA end-diastolic blood velocity observed three months after finish of the infusion therapy.

[The influence of water soluble antioxidant agent (mexidol) on optic nerve and blood flow velocity in ocular and orbital arteries in patients with primary open-angle glaucoma].

The prospective single-blind placebo-controlled randomized trial is devoted to influence of mexidol (2-ethil-6-methil-3-hydroxipiridine succinate) on dynamics of optic nerve electrophysiologic profile and velocity indices of blood flow in ocular and orbital arteries in correlation with changes of retinal photosensitivity, visual acuity and visual field size during course of intravenous mexidol infusions and standard treatment of primary open-angle glaucoma. 2 weeks of intravenous infusions of 300 mg mexidol daily was found to cause depression of optic nerve electrical sensitivity threshold and widening of total visual field (16 mm2 test stimulus) after 14 days of treatment. These effects were not associated with changes of blood flow velocity in ocular and orbital arteries, were transient and came to initial indices 3 months after the end of treatment.

[Changes in the ocular and orbital blood flow in patients with retinal detachment treated surgically].

Sixty-eight patients with dystrophic regmatogenic detachment of the retina and 78 controls with different clinical refraction were examined by triplex scanning of the eyeball. Bloodflow parameters in the orbital artery, central retinal artery, posterior short ciliary arteries were evaluated before and in various periods after the operation. Characteristics of the bloodflow in the ocular and orbital arteries in myopia, detachment of the retina in the presence of myopic and emmetropic refraction, proliferative vitreoretinopathy of various degrees and patterns of its progress during the postoperative period were determined and time course of bloodflow parameters evaluated in some types of interventions.