[Effects of human cultural neuronal and mesenchymal stem cells on the rat learning and brain state after acute hypoxia].

The aim of the study was to compare the effects of neurotransplantation of cultural neural stem cells (NSC) and mesenchymal stem cells (MSC) on the rat behaviour and brain state after acute hypoxia. It was shown that development of two-way avoidance defensive conditioning in a shuttle box improved in rats-recipients with NSC, but not MSC as compared to control. Both the transplants of NSC and transplants of MSC exert neuroprotective influence on the rat brain.

[Monitoring for influenza in population of Western Siberia in 2007-2009].

Aim: To analyze influenza viruses isolated in the 2008-2009 autumn-winter season, and to test sera collected in the south of Western Siberia during the beginning and the end of the epidemic seasons from 2007 until the A/H1N1 pandemic.

Materials And Methods: Total 149 clinical samples were analyzed and 2190 blood sera were tested. During the 2008-2009 season 17 influenza viruses were isolated.

[Detection of antibodies to A/H5N1 influenza virus in citizens of Russian Federation].

Aim: To determine levels of antibodies to influenza virus A/H5N1 in serum samples of people living in different regions of Russia in order to assess the risk of infection with avian influenza H5N1.

Materials And Methods: Two thousand one hundred sixty-eight serum samples were tested by hemagglutination inhibition assay for the presence of antibodies to influenza virus A/H5N1.

Results: Twenty-six serum samples obtained from residents of Khanty-Mansiysk Autonomous Area and 2 samples from residents of Novosibirsk region were positive for antibodies to serotype A/H5.

[Characteristic of high pathogenic avian influenza virus subtype H5N1 isolated from common gull (Larus canus)].

Aim: To study biological characteristics of H5N1 influenza virus isolated from common gull on south of West Siberia in 2006.

Materials And Methods: Isolation and characterization of biological characteristics performed according to recommendations of World Health Organization.

Results: Influenza virus A (H5N1) was first isolated from common gull (Larus canus) in Russia.

[Hemagglutination inhibition test for retrospective diagnosis of avian influenza in mammals].

Aim: To compare usage of native and formalinized erythrocytes from different animal species in hemagglutination inhibition (HI) test for detection of level of specific antibodies to H5N1 influenza virus in sera of mammals.

Materials And Methods: Level of anti-H5 antibodies to influenza H5 control antigen and to influenza viruses A/Common gull/Chany/2006 (H5N1), A/duck/Tuva/01/06 (H5N1), A/Anas platyrhynchos/Chany Lake/9/03 (H5N3) was determined by hemagglutination inhibition test in two influenza A (H5) reference antisera as well as in ferret antisera to native strains of avian influenza virus. Equine, rhesus macaque, sheep, guinea pig, goose, and chicken erythrocytes were used.