[The use of acetylcysteine in the combined treatment of patients with acute 1,2-dichloroethane poisoning].

The authors analyse the use of acetylcysteine as specific antidote treatment in 37 patients with acute 1,2-dichlorethane (DCE) poisoning. Administration of dichlorethane did not produce any determining effect on the outcome of the treatment in critical and irreversible concentration of DCE in the blood. The main component in complex therapy is early hemosorption.

[Hemosorption in the combined treatment of patients with acute exogenous poisonings].

The authors analyze their experience with 247 hemosorptions in 163 patients with acute exogenous poisonings. Indications and contraindications to hemosorption in these patients are described. Methodical aspects of hemosorption are described: vascular approaches, apparatus, prehemosorption care, regimens of hemosorption.

[Tactics and emergency aid in acute chemical poisoning].

Successful treatment of acute intoxications should include early urgent measures, use of specific antidotes, polysymptomatic and polysyndromic treatment. It is an error to delay intensive care until laboratory identification of the toxicant. Only combined use of methods directed to potentiate natural urocesses, intra--and extracorporal detoxication allows to improve treatment results of treating acute intoxications.

[Hemosorption in the combined treatment of acute 1,2-dichloroethane poisonings].

Carbon hemosorption was carried out in 41 patients suffering of 1,2-dichlorethane intoxication (acute). Complex methods of therapy included also methods of potentiation of natural processes of detoxication, enterosorption, specific antidote treatment with acetylcysteine and vitamin E. Use of hemosorption favoured essential reduction of lethality, decrease of the number of severe complications (exotoxic shock, hepatopathy).

[Cholinesterase reactivators in the combined treatment of patients with acute organophosphate insecticide poisonings].

The efficacy of different cholinesterase reactivators (alloxyme, dietixyme, dipiroxyme, isonitrosine) used as specific antidotes) was evaluated in 78 patients with acute intoxications by phosphorus-organic insecticides. The most pronounced clinical effect was obtained with use of alloxyme and dietixyme. The number of side-effects was observed during employment of dietixyme.