Publications by authors named "O V Kovalchuk"

Chemotherapy is a therapy of choice for many cancers. However, it is often inefficient for long-term patient survival and is usually accompanied by multiple adverse effects. The adverse effects are mainly associated with toxicity to normal cells, frequently resulting in immune system depression, nausea, loss of appetite and metabolic changes.

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Objectives: This study aimed to understand the current state of continuing professional development (CPD) for rehabilitation professionals globally and identify perceived requirements to enhance education to guide efforts to develop internationally relevant, interprofessional, rehabilitation coursework adaptable to the various professions and contexts to support workforce development.

Design: This was a mixed methods, exploratory study. A convenience sample of rehabilitation professionals received surveys regarding current access to CPD and the perceived needs for additional resources to support professional development.

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Climatic oscillations are considered primary factors influencing the distribution of various life forms on Earth. Large species adapted to cold climates are particularly vulnerable to extinction due to climate changes. In our study, we investigated whether temperature increase since the Late Pleistocene and the contraction of environmental niche during the Holocene were the main factors contributing to the decreasing range of moose (Alces alces) in Europe.

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Article Synopsis
  • The β-cells in the pancreas are crucial for insulin production and are affected by factors like obesity and insulin resistance, leading to Type 2 Diabetes (T2D).
  • β-cell dedifferentiation and transdifferentiation, where these cells lose their specialized functions and change into other cell types, significantly worsen T2D more than just the loss of β-cells.
  • Research is focusing on understanding the mechanisms of this dedifferentiation process and exploring potential treatments that could target it to better manage T2D.
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The aim of the article is to analyze the legal aspects and mechanisms of confidential medical information protection about an individual in the health care sphere in Ukraine. During the scientific research, various methods of cognition of legal phenomena were used. Among the general scientific approaches, the dialectical method was primarily used, which allowed to identify trends in the development of patient information rights and formulate proposals for improving legislation in the field of medical data protection.

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