Publications by authors named "O V Kolesnik"

Article Synopsis
  • - The study investigated the combination of pembrolizumab and epacadostat as a treatment for advanced non-small cell lung cancer (NSCLC) patients with high PD-L1 expression, aiming to see if it improved outcomes compared to pembrolizumab alone.
  • - A total of 154 patients were involved, showing similar overall response rates (32.5% for combination vs. 39.0% for control) and comparable progression-free survival (around 6.7 months for combination vs. 6.2 months for control).
  • - Notably, while the combination treatment led to a decrease in circulating kynurenine levels, common serious side effects included pneumonia and anemia; most patients did not normalize kynurenine
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Objective: The aim: To find out the features of the hip circumference in the middle of both extremities by students of higher education institutions of Bukovina, depending on the sport type.

Patients And Methods: Materials and methods: The study of anthropometric parameters was conducted on 115 students of higher education institutions of Bukovina from 16 to 18 years where 78 (67.82%) - young boys and 37 (32.

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Objective: The aim: The aim of the study is the clinical-pathogenetic reasoning of vestibular dysfunctions (VD) development against the background of chronic brain ischemia in the presence of degenerative changes in the cervical spine (CS) in the post COVID period.

Patients And Methods: Materials and methods: 82 patients, in the conditions of the clinical base of the Odessa National Medical University in 2019-2021 were examined. Group I with VD against the background of chronic brain ischemia (CBI) at the compensated phase; Group II with VD against the background of CBI at the subcom¬pensated phase (33 men; 49 women), aged from 18 to 55 years.

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We used Jones-matrix images of protein networks of blood plasma films obtained from laser autofluorescence and determined the sensitivity, specificity, accuracy, and prognostication of positive and negative results. Our study aimed (1) to develop and substantiate new approaches for the diagnosis of endometriosis by improving the methods of Jones-matrix mapping of laser-induced auto-fluorescence and (2) to develop statistical approaches for analyzing the distribution of values of the true component of Jones-matrix images of blood plasma. Biological preparations were performed for two groups: 35 samples from control group 1 (women with infertility of unknown origin) and 85 samples from group 2 with endometriosis (women with infertility and endometriosis).

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Radioactive contaminants create problems all over world, involving marine ecosystems, with their ecological importance increasing in the future. The review focuses on bioeffects of a series of alpha and beta emitting radioisotopes (americium-241, uranium-(235 + 238), thorium-232, and tritium) and gamma radiation. Low-intensity exposures are under special consideration.

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