Antibacterial Bionanocomposites Based on Drug-Templated Bifunctional Mesoporous Silica Nanocontainers.

The creation of antibacterial nanocomposites that provide prolonged release of encapsulated drugs is of great interest for various fields of medicine (dentistry, tissue regeneration, etc.). This article demonstrates the possibility of creating such nanocomposites based on sodium alginate and drug-templated mesoporous silica nanocontainers (MSNs) loaded with two bioactive substances.

Structuring of Surface Films Formed on Magnesium in Hot Chlorobenzotriazole Vapors.

Chamberprotection of metals from atmospheric corrosion is a variety of vapor-phase inhibition. It is based on the effect of adsorption films formed in the vapors of low-volatile corrosion inhibitors at elevated temperatures. The paper analyzes the specific features of the chamber protection of a magnesium alloy with chlorobenzotriazole.

Impact of the Spectral Composition of Kilovoltage X-rays on High-Z Nanoparticle-Assisted Dose Enhancement.

Nanoparticles (NPs) with a high atomic number () are promising radiosensitizers for cancer therapy. However, the dependence of their efficacy on irradiation conditions is still unclear. In the present work, 11 different metal and metal oxide NPs (from Cu ( = 29) to BiO ( = 83)) were studied in terms of their ability to enhance the absorbed dose in combination with 237 X-ray spectra generated at a 30-300 kVp voltage using various filtration systems and anode materials.

Radiosensitization by Gold Nanoparticles: Impact of the Size, Dose Rate, and Photon Energy.

Gold nanoparticles (GNPs) emerged as promising antitumor radiosensitizers. However, the complex dependence of GNPs radiosensitization on the irradiation conditions remains unclear. In the present study, we investigated the impacts of the dose rate and photon energy on damage of the pBR322 plasmid DNA exposed to X-rays in the presence of 12 nm, 15 nm, 21 nm, and 26 nm GNPs.

Drug-templated mesoporous silica nanocontainers with extra high payload and controlled release rate.

The possibility of one-step creating of pH-sensitive mesostructured silica-based nanocontainers with exceptionally high payload using associates of two antiseptics (including hydrolyzable one) as templates is demonstrated. The effects of the template nature and the conditions of the sol-gel process on the porous structure of silica nanocontainers are studied and discussed. The kinetics of the templating drug release from such containers is studied and some features of this process are analyzed.