[The clinical/laboratory support for using melatonin in chronic cerebrovascular diseases and metabolic syndrome].

Aim: To evaluate a role of melatonin deficiency in the metabolic syndrome and chronic cerebral ischemia (CCI).

Material And Methods: One hundred and seventy-nine men, aged 45-75 years, with CCI and components of metabolic syndrome (MS) were examined. Intima-media thickness (IMT) in the carotid arteries and cerebrovascular reactivity was assessed by the results of duplex scanning and hypercapnic test.

[A role of insomnia in the development of silent cerebral infarctions].

Aim: To investigate the relationship between insomnia, hemostatic abnormalities and silent cerebral infarctions.

Material And Methods: A complex study of 76 male patients, aged 40-85, with vascular risk factors was carried out. Magnetic resonance imaging (MRI) data was used to verify presence of silent cerebral infarctions; the presence and severity of insomnia were determined using questionnaires and polysomnography.