[PROBLEMS TOWARDS MEASLES ELIMINATION IN RUSSIAN FEDERATION].

Introduction of live measles vaccines into daily practice resulted in a pronounced reduction of measles morbidity in many countries, that allowed WHO to develop the measles eradication program. Russian Federation has commenced realization of the eradication program for local measles cases in the country, (measles elimination) in 2002. and had achieved significant success by 2007.

[Epidemiologic control for rubella in pregnant women].

Aim: Evaluate effectiveness of measures specified by epidemiologic control for rubella in pregnant women.

Materials And Methods: 585 pregnant women with suspected measles were laboratory examined in 10 Regional Centers of Control for Measles and Rubella by EIA.

Results: 24 rubella infected pregnant women aged 16-36 years were detected among the examined pregnant women, most of those (91.

[Tactics of measles epidemiologic surveillance during elimination period].

Aim: Evaluation of effectiveness of new tactics of measles epidemiologic control in measles elimination in Russian Federation.

Materials And Methods: Analysis of active search of measles patients among patients with fever and maculopapular rash is presented. Range of primary diagnosis and rate of detection of measles cases is studied.

Progress toward measles elimination in the Russian Federation, 2003-2009.

Successful implementation of the Russian Federation's national measles elimination program has been ensured by high vaccine coverage (>95%) of the target population (with 2 doses of measles-containing vaccine), case-based laboratory investigation of measles, and active surveillance of measles cases among patients with rashes and/or fever. As a result, the incidence of measles has decreased to <1 case per 1,000,000 population (2007-2009); no circulation of D6 genotype, which was endemic in the Russian Federation, has been observed since the second half of 2007; and the proportion of imported measles cases of different genotypes increased to 19.8% in 2007 from 1% in 2003.

Genetic variability of wild-type measles viruses, circulating in the Russian Federation during the implementation of the National Measles Elimination Program, 2003-2007.

Genetic characterization of wild-type measles viruses (MVs) is an important component of laboratory surveillance of measles. In this study, a phylogenetic analysis was performed of the nucleoprotein gene sequences of 228 MVs isolated in the Russian Federation between 2003 and 2007. Five genotypes, D4, D5, D6, D8, and H1, were detected.