Publications by authors named "O Toubas"
We report a case of classic HSE with early neurological relapse 7 days after onset of acyclovir treatment secondary to cerebral venous thrombosis (CVT). The development of CVT after meningoencephalitis has been described with neurotropic viruses such as HSV, HIV, or enteroviruses and also bacterial or fungal agents. CVT is probably the consequence of the inflammation secondary to these infections.
View Article and Find Full Text PDFIdelalisib is a potent and selective inhibitor of the PI3Kδ approved since September 2014 for the treatment of several types of B cell malignancies. Pulmonary adverse events related to idelalisib are an emerging serious adverse event. We report here a single centre cohort of 16 patients who initiated idelalisib as routine treatment.
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- - Organizing pneumonia (OP) is characterized by granulation tissue blocking small airways and can be classified as either cryptogenic (COP) or secondary to lung injuries.
- - A case study on a 38-year-old male smoker with COP reveals that patients typically present with diffuse micronodules on CT scans and show a subacute clinical pattern with specific radiological features.
- - Effective treatment with steroid therapy led to symptom improvement and radiological resolution in all cases studied, emphasizing the need to properly diagnose and differentiate MNOP from other similar conditions for timely treatment.
Rosai-Dorfman Disease (RDD) is a rare non-neoplastic entity, also known as sinus histiocytosis with massive lymphadenopathy (SHML), characterized by a benign proliferation of histiocytes in lymph nodes. Localized forms of RDD involving the tracheobronchial tree are very rare. There is no consensus regarding the management of central airway forms and recurrence is frequent.
View Article and Find Full Text PDFBackground: Diffusion-weighted imaging (DWI) fluid-attenuated inversion recovery (FLAIR) mismatch has a proven ability to estimate stroke-to-magnetic resonance imaging (MRI) delay. We evaluated the possibility of enhancing this estimation by quantifying MRI (DWI and FLAIR) signals, and compared this approach to the visual evaluation of DWI-FLAIR mismatch.
Materials And Methods: This retrospective study included 194 patients presenting an ischemic stroke in the middle cerebral artery territory that had been explored with 3T MRI within 12h.