Publications by authors named "O T-Y Tsang"
Article Synopsis
- Post-COVID-19, there's an increased risk of mpox infection for vulnerable groups like men who have sex with men (MSM) and people living with HIV, especially as international travel resumes.* -
- In Hong Kong, free mpox vaccinations target high-risk individuals, revealing that while many MSM feel a strong need to protect their partners, stigma around mpox symptoms is also a significant concern.* -
- Although MSM in HIV care are less sexually active than those at vaccination sites, they report higher recent STI diagnoses and perceived exposure risks, indicating the need for accessible vaccination options for varied risk behaviors.*
Background: Patients with COVID-19 display a broad spectrum of manifestations from asymptomatic to life-threatening disease with dysregulated immune responses. Mechanisms underlying the detrimental immune responses and disease severity remain elusive.
Methods: We investigated a total of 137 APs infected with SARS-CoV-2.
Objectives: To assess impacts of early detection and prompt antiretroviral therapy (ART) on the latest epidemiologic situation to inform intervention strategy.
Methods: We analysed data from two clinical cohorts in Hong Kong where sexual transmission accounted for the majority of HIV infections. The two cohorts comprised patients newly diagnosed in 2007-2008 and 2016-2018 respectively.
The antibody response magnitude and kinetics may impact clinical severity, serological diagnosis and long-term protection of COVID-19, which may play a role in why children experience lower morbidity. We therefore tested samples from 122 children in Hong Kong with symptomatic (n = 78) and asymptomatic (n = 44) SARS-CoV-2 infections up to 200 days post infection, relative to 71 infected adults (symptomatic n = 61, and asymptomatic n = 10), and negative controls (n = 48). We assessed serum IgG antibodies to a 14-wide antigen panel of structural and accessory proteins by Luciferase Immuno-Precipitation System (LIPS) assay and circulating cytokines.
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