Publications by authors named "O T Wong"

Article Synopsis
  • This study investigated the use of MR-guided radiotherapy (MRgRT) for prostate cancer patients who had undergone surgery, focusing on its clinical outcomes and patient tolerability.
  • A total of 30 patients received adaptive MRgRT and were monitored for progression-free survival (PFS) and adverse events over an average follow-up period of around 32 months.
  • The results indicated high PFS rates (96.4% at 2 years, 78.8% at 3 years) and low rates of significant side effects, suggesting MRgRT is effective and well-tolerated in this patient group.
View Article and Find Full Text PDF
Article Synopsis
  • The study investigates differences in sleep architecture among children with narcolepsy, idiopathic hypersomnia (IH), and those who are subjectively sleepy, aiming to improve diagnostic methods.
  • It involved 28 children with narcolepsy, 11 with IH, and 26 control subjects, analyzing sleep stability and disturbance through polysomnography and multiple sleep latency tests (MSLT).
  • Results showed narcoleptic children had more frequent wake transitions and shorter REM episode durations compared to the other groups, suggesting that specific sleep patterns could help differentiate between these sleep disorders in children.
View Article and Find Full Text PDF

Accumulating evidence suggests that gut microbiota alterations influence brain function and could serve as diagnostic biomarkers and therapeutic targets. The potential of using fecal microbiota signatures to aid autism spectrum disorder (ASD) detection is still not fully explored. Here, we assessed the potential of different levels of microbial markers (taxonomy and genome) in distinguishing children with ASD from age and gender-matched typically developing peers ( = 598, ASD vs TD = 273 vs 325).

View Article and Find Full Text PDF

Borderline personality disorder (BPD) is a complex and severe psychiatric condition characterized by emotional, self-image, behavior, and relational instability. While adult BPD heterogeneity has been extensively studied, the phenomenological borderline personality features (BPFs) in adolescence remain uninvestigated. This study aimed to explore the potentially dynamic causal relationships between BPFs in adolescence and identify the subtypes through cross-lagged panel network (CLPN) analysis.

View Article and Find Full Text PDF