Publications by authors named "O T Wiebenga"
Article Synopsis
- Silicone breast implants often face issues like ruptures and gel bleed, and while MRI is seen as the best imaging method, recent studies indicate that ultrasound might also be effective.
- This study involved 104 women who underwent both ultrasound and MRI on the same day, with radiologists evaluating the results for accuracy in detecting implant ruptures and silicone deposits in lymph nodes.
- Findings revealed that ultrasound was highly accurate (96%) for detecting ruptures and was better than MRI for finding silicone in lymph nodes, leading to a recommendation to start examinations with ultrasound before using MRI if needed.
Background: Multiple sclerosis is characterized by white matter lesions, which are visualized with conventional T2-weighted magnetic resonance imaging (MRI). Little is known about local metabolic processes preceding the appearance and during the pathological development of new lesions.
Objective: To identify metabolite changes preceding white matter (WM) lesions and pathological severity of lesions over time.
Background And Purpose: Natalizumab treatment strongly affects relapsing-remitting multiple sclerosis, possibly by restraining white matter damage. This study investigated changes in white matter diffusivity in patients with relapsing-remitting multiple sclerosis during their first year of natalizumab treatment by using diffusion tensor imaging.
Materials And Methods: The study included patients with relapsing-remitting multiple sclerosis initiating natalizumab at baseline (n = 22), patients with relapsing-remitting multiple sclerosis continuing interferon-β or glatiramer acetate (n = 17), and healthy controls (n = 12).
Background And Purpose: The considerable clinical effect of natalizumab in patients with relapsing-remitting multiple sclerosis might be explained by its possible beneficial effect on axonal functioning. In this longitudinal study, the effect of natalizumab on absolute concentrations of total N-acetylaspartate, a marker for neuronal integrity, and other brain metabolites is investigated in patients with relapsing-remitting multiple sclerosis by using MR spectroscopic imaging.
Materials And Methods: In this explorative observational study, 25 patients with relapsing-remitting multiple sclerosis initiating natalizumab treatment were included and scanned every 6 months for 18 months.
The purpose of this study was to evaluate quality parameters, metabolite concentrations and concentration ratios, and to investigate the reproducibility of quantitative proton magnetic resonance spectroscopic imaging ((1)H-MRSI) of selected white and gray matter regions of healthy adults. 2D-quantitative short-TE (1)H-MRSI spectra were obtained at 1.5T from the healthy human brain.
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