Publications by authors named "O T Sykes"

Background: Participants in Alzheimer's disease (AD) prevention studies are generally required to enroll with a study partner; this requirement constitutes a barrier to enrollment for some otherwise interested individuals. Analysis of dyads enrolled in actual AD trials suggests that the study partner requirement shapes the population under study.

Objective: To understand if individuals can identify someone to serve as their study partner and whether they would be willing to ask that individual.

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Objective: Assess caregivers' knowledge about juice and sugar-sweetened beverages (SSBs) and identify factors that contribute to their early introduction.

Methods: One hundred forty-four parents of young infants completed a 45-item questionnaire focused on infant nutrition.

Results: Seventy-two percent of parents plan to give juice to their babies starting in the first year of life; only 16% plan to introduce SSBs.

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Diabetic kidney disease (DKD) is one of the leading pathological causes of decreased renal function and progression to end-stage kidney failure. To explore and characterize age-related changes in DKD and associated glomerular damage, we used a rat model of type 2 diabetic nephropathy (T2DN) at 12 wk and older than 48 wk. We compared their disease progression with control nondiabetic Wistar and diabetic Goto-Kakizaki (GK) rats.

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